Effects of methylphenidate and d-amphetamine on timing in the rat.

Eckerman, D A; Segbefia, D; Manning, S; Breese, G S

Eckerman, D A; Segbefia, D; Manning, S; Breese, G S.

Afiliación

Eckerman DA; University of North Carolina, Chapel Hill 27514.

Pharmacol Biochem Behav ; 27(3): 513-5, 1987 Jul.

Article en En | MEDLINE | ID: mdl-3659073

RESUMEN

Rats were trained to press a lever for food pellets provided according to a fixed interval 60-sec schedule of reinforcement. Probe trials (peak trials) assessed responding over two-min periods with no pellet delivered. The low rates of responding found early and late in probe trials were increased by methylphenidate and 1.0 mg/kg d-amphetamine (rate-dependent effect). Further, the mean time of responding (peak time) was shortened for both drugs (timing effect).

Asunto(s)

Condicionamiento Operante/efectos de los fármacos; Dextroanfetamina/farmacología; Metilfenidato/farmacología; Percepción del Tiempo/efectos de los fármacos; Animales; Conducta Animal/efectos de los fármacos; Masculino; Ratas; Ratas Endogámicas; Tiempo de Reacción/efectos de los fármacos

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Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Percepción del Tiempo / Condicionamiento Operante / Dextroanfetamina / Metilfenidato Límite: Animals Idioma: En Revista: Pharmacol Biochem Behav Año: 1987 Tipo del documento: Article Pais de publicación: Estados Unidos

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