Toxic effect and inability of L-homoserine to be a nitrogen source for growth of <i>Escherichia coli</i> resolved by a combination of <i>in vivo</i> evolution engineering and omics analyses.

Alkim, Ceren; Farias, Daniele; Fredonnet, Julie; Serrano-Bataille, Helene; Herviou, Pauline; Picot, Marc; Slama, Nawel; Dejean, Sebastien; Morin, Nicolas; Enjalbert, Brice; François, Jean M

Toxic effect and inability of L-homoserine to be a nitrogen source for growth of Escherichia coli resolved by a combination of in vivo evolution engineering and omics analyses.

Alkim, Ceren; Farias, Daniele; Fredonnet, Julie; Serrano-Bataille, Helene; Herviou, Pauline; Picot, Marc; Slama, Nawel; Dejean, Sebastien; Morin, Nicolas; Enjalbert, Brice; François, Jean M.

Afiliación

Alkim C; Toulouse Biotechnology Institute (TBI), Université de Toulouse, CNRS, INRA, INSA, Toulouse, France.
Farias D; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Fredonnet J; Toulouse Biotechnology Institute (TBI), Université de Toulouse, CNRS, INRA, INSA, Toulouse, France.
Serrano-Bataille H; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Herviou P; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Picot M; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Slama N; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Dejean S; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
Morin N; Institut de Mathématique Toulouse, Toulouse, France.
Enjalbert B; Toulouse White Biotechnology Center (TWB), UMS-INSA-INRA-CNRS, Toulouse, France.
François JM; Toulouse Biotechnology Institute (TBI), Université de Toulouse, CNRS, INRA, INSA, Toulouse, France.

Front Microbiol ; 13: 1051425, 2022.

Article en En | MEDLINE | ID: mdl-36583047

Palabras clave

Escherichia coli; L-homoserine; evolutionary engineering; genetic regulation; microbial physiology; transcriptomics

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Microbiol Año: 2022 Tipo del documento: Article País de afiliación: Francia Pais de publicación: Suiza

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