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The Role of Novel Antibiotics in the Management of Diabetic Foot Infection.
Mougakou, Efterpi; Mastrogianni, Elpida; Kyziroglou, Maria; Tziomalos, Konstantinos.
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  • Mougakou E; Second Department of Internal Medicine, Sismanogleio Hospital, Athens, Greece.
  • Mastrogianni E; First Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Laiko General Hospital, Athens, Greece.
  • Kyziroglou M; First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 54636, Thessaloniki, Greece.
  • Tziomalos K; First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 54636, Thessaloniki, Greece. ktziomalos@yahoo.com.
Diabetes Ther ; 14(2): 251-263, 2023 Feb.
Article en En | MEDLINE | ID: mdl-36565422
Diabetic foot infection is a frequent and potentially life-threatening complication of diabetes mellitus. Antibiotic treatment is the cornerstone of management of diabetic foot infection but the rising prevalence of antibiotic resistance has resulted in increasing rates of treatment failure. In this context, the development of several novel antibiotics might represent a useful tool in severe diabetic foot infections caused by multidrug-resistant bacteria. In the present review, we summarize the safety and efficacy of novel antibiotics in patients with diabetic foot infection. Relevant data are limited, and randomized controlled studies that evaluated the role of these agents in this field are lacking. Until more robust data are available, cefiderocol and dalbavancin, which have been studied more extensively in patients with bone infections, might be attractive options in carefully selected patients with severe diabetic foot infection.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Risk_factors_studies Idioma: En Revista: Diabetes Ther Año: 2023 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Risk_factors_studies Idioma: En Revista: Diabetes Ther Año: 2023 Tipo del documento: Article País de afiliación: Grecia Pais de publicación: Estados Unidos