miR-142-3p improves paclitaxel sensitivity in resistant breast cancer by inhibiting autophagy through the GNB2-AKT-mTOR Pathway.

Shi, Yingxiang; Wang, Jing; Tao, Shuang; Zhang, Shiwen; Mao, Lingyu; Shi, Xiuru; Wang, Wenrui; Cheng, Changjie; Shi, Yurong; Yang, Qingling

Shi, Yingxiang; Wang, Jing; Tao, Shuang; Zhang, Shiwen; Mao, Lingyu; Shi, Xiuru; Wang, Wenrui; Cheng, Changjie; Shi, Yurong; Yang, Qingling.

Afiliación

Shi Y; Anhui Province Key Laboratory of Translational Cancer Research (Bengbu Medical College), Bengbu, China.
Wang J; Anhui Province Key Laboratory of Translational Cancer Research (Bengbu Medical College), Bengbu, China.
Tao S; Anhui Province Key Laboratory of Translational Cancer Research (Bengbu Medical College), Bengbu, China.
Zhang S; Department of Life Sciences, Bengbu Medical College, Anhui 233030, China.
Mao L; Department of Life Sciences, Bengbu Medical College, Anhui 233030, China.
Shi X; Anhui Province Key Laboratory of Translational Cancer Research (Bengbu Medical College), Bengbu, China.
Wang W; Department of Biotechnology, Bengbu Medical College, Anhui 233030, China.
Cheng C; Department of Biochemistry and Molecular Biology, Bengbu Medical College, Anhui 233030, China.
Shi Y; Department of Biochemistry and Molecular Biology, Bengbu Medical College, Anhui 233030, China. Electronic address: shiyr@126.com.
Yang Q; Department of Biochemistry and Molecular Biology, Bengbu Medical College, Anhui 233030, China. Electronic address: yqlmimi@163.com.

Cell Signal ; 103: 110566, 2023 Mar.

Article en En | MEDLINE | ID: mdl-36539001

Asunto(s)

Neoplasias de la Mama; MicroARNs; Femenino; Humanos; Autofagia; Neoplasias de la Mama/tratamiento farmacológico; Neoplasias de la Mama/genética; Línea Celular Tumoral; Resistencia a Antineoplásicos/genética; Regulación Neoplásica de la Expresión Génica; Proteínas de Unión al GTP/metabolismo; MicroARNs/genética; MicroARNs/metabolismo; Paclitaxel/farmacología; Paclitaxel/uso terapéutico; Proteínas Proto-Oncogénicas c-akt/metabolismo; Serina-Treonina Quinasas TOR/metabolismo

Palabras clave

Autophagy; Breast cancer; GNB2; Paclitaxel resistance; miR-142-3p

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / MicroARNs Tipo de estudio: Diagnostic_studies Límite: Female / Humans Idioma: En Revista: Cell Signal Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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