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Pancreatoduodenectomy following neoadjuvant chemotherapy in duodenal adenocarcinoma.
Seo, Dongjin; Park, Bo Gyeom; Jung, Dawn; Hwang, Ho Kyoung; Kim, Sung Hyun; Hong, Seung Soo; Kang, Chang Moo.
Afiliación
  • Seo D; Yonsei University College of Medicine, Seoul, Korea.
  • Park BG; Yonsei University College of Medicine, Seoul, Korea.
  • Jung D; Yonsei University College of Medicine, Seoul, Korea.
  • Hwang HK; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • Kim SH; Yonsei University College of Medicine, Seoul, Korea.
  • Hong SS; Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.
  • Kang CM; Pancreatobiliary Cancer Center, Yonsei Cancer Center, Severance Hospital, Seoul, Korea.
Ann Hepatobiliary Pancreat Surg ; 27(1): 114-119, 2023 Feb 28.
Article en En | MEDLINE | ID: mdl-36536505
A 51-year-old male patient had four times of massive hematochezia episode three days before arrival. Carbohydrate antigen (CA) 19-9 level was extremely elevated. Computed tomography, magnetic resonance imaging, and positron emission tomography-computed tomography identified 5.7 cm sized periampullary duodenal cancer with regional metastatic lymph nodes and vascular invasion to aberrant right hepatic artery, main portal vein, and superior mesenteric vein. Diagnosed as duodenal adenocarcinoma through endoscopic biopsy, 16 times of FOLFIRI (5-fluorouracil, leucovorin, irinotecan) was conducted. The regimen changed to XELOX (capecitabine, oxaliplatine), four times of administration was done, and the CA19-9 level dramatically decreased. The tumor decreased to 2.1 cm. After R0 laparoscopic pylorus preserving pancreatoduodenectomy, no adjuvant therapy was given. No sign of recurrence or metastasis was reported, and the patient reached complete remission after five years. We reported a case where neoadjuvant chemotherapy for locally advanced duodenal adenocarcinoma was shown to be effective.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Ann Hepatobiliary Pancreat Surg Año: 2023 Tipo del documento: Article Pais de publicación: Corea del Sur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Ann Hepatobiliary Pancreat Surg Año: 2023 Tipo del documento: Article Pais de publicación: Corea del Sur