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Assessing the individual benefits of reducing HIV diagnosis delay and increasing adherence to HIV care and treatment.
Uzun Jacobson, Evin; Li, Zihao; Bingham, Adrienna; Farnham, Paul G; Sansom, Stephanie L.
Afiliación
  • Uzun Jacobson E; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Li Z; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Bingham A; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Farnham PG; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
  • Sansom SL; Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.
AIDS Care ; 35(7): 1007-1013, 2023 07.
Article en En | MEDLINE | ID: mdl-36524868
We used an agent-based simulation model (Progression and Transmission of HIV) to follow for 20 years a cohort of persons in the United States infected with HIV in 2015. We assessed the benefits of reducing the delay between HIV infection and diagnosis and increasing adherence to HIV care and treatment on the percent of persons surviving 20 years after infection, average annual HIV transmission rates, and time spent virally suppressed. We examined average diagnosis delays of 1.0-7.0 years, monthly care drop-out rates of 5% to 0.1%, and combinations of these strategies. The percent of the cohort surviving the first 20 years of infection varied from 70.8% to 77.5%, and the annual transmission risk, from 1.5 to 5.2 HIV transmissions per 100 person-years. Thus, individuals can enhance their survival and reduce their risk of transmission to partners by frequent testing for HIV and adhering to care and treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH Tipo de estudio: Diagnostic_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: AIDS Care Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por VIH Tipo de estudio: Diagnostic_studies Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: AIDS Care Asunto de la revista: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido