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Brain metastatic outgrowth and osimertinib resistance are potentiated by RhoA in EGFR-mutant lung cancer.
Adua, Sally J; Arnal-Estapé, Anna; Zhao, Minghui; Qi, Bowen; Liu, Zongzhi Z; Kravitz, Carolyn; Hulme, Heather; Strittmatter, Nicole; López-Giráldez, Francesc; Chande, Sampada; Albert, Alexandra E; Melnick, Mary-Ann; Hu, Bomiao; Politi, Katerina; Chiang, Veronica; Colclough, Nicola; Goodwin, Richard J A; Cross, Darren; Smith, Paul; Nguyen, Don X.
Afiliación
  • Adua SJ; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Arnal-Estapé A; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Zhao M; Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Qi B; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Liu ZZ; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Kravitz C; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Hulme H; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Strittmatter N; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, AstraZeneca, Cambridge, UK.
  • López-Giráldez F; Imaging and Data Analytics, Clinical Pharmacology and Safety Sciences, AstraZeneca, Cambridge, UK.
  • Chande S; Yale Center for Genome Analysis, Yale University School of Medicine, New Haven, CT, USA.
  • Albert AE; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Melnick MA; Department of Cell Biology, Yale School of Medicine, New Haven, CT, USA.
  • Hu B; Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Politi K; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Chiang V; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.
  • Colclough N; Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Goodwin RJA; Department of Medicine (Medical Oncology), Yale University School of Medicine, New Haven, CT, USA.
  • Cross D; Yale Cancer Center, Yale University School of Medicine, New Haven, CT, USA.
  • Smith P; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.
  • Nguyen DX; DMPK, Early Oncology TDE, AstraZeneca, Cambridge, UK.
Nat Commun ; 13(1): 7690, 2022 12 12.
Article en En | MEDLINE | ID: mdl-36509758
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido