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Towards a Genetic Linkage Map of the California Condor, an Endangered New World Vulture Species.
Romanov, Michael N; Da, Yang; Chemnick, Leona G; Thomas, Steven M; Dandekar, Sugandha S; Papp, Jeanette C; Ryder, Oliver A.
Afiliación
  • Romanov MN; Conservation Genetics, Beckman Center for Conservation Research, San Diego Zoo Wildlife Alliance, Escondido, CA 92027, USA.
  • Da Y; Department of Animal Science, University of Minnesota, Saint Paul, MN 55108, USA.
  • Chemnick LG; Conservation Genetics, Beckman Center for Conservation Research, San Diego Zoo Wildlife Alliance, Escondido, CA 92027, USA.
  • Thomas SM; Conservation Genetics, Beckman Center for Conservation Research, San Diego Zoo Wildlife Alliance, Escondido, CA 92027, USA.
  • Dandekar SS; Human Genetics Department, GenoSeq Core, University of California, Los Angeles, CA 90095, USA.
  • Papp JC; Human Genetics Department, GenoSeq Core, University of California, Los Angeles, CA 90095, USA.
  • Ryder OA; Conservation Genetics, Beckman Center for Conservation Research, San Diego Zoo Wildlife Alliance, Escondido, CA 92027, USA.
Animals (Basel) ; 12(23)2022 Nov 24.
Article en En | MEDLINE | ID: mdl-36496789
The development of a linkage map is an important component for promoting genetic and genomic studies in California condors, an endangered New World vulture species. Using a set of designed anonymous microsatellite markers, we genotyped a reference condor population involving 121 individuals. After marker validation and genotype filtering, the genetic linkage analysis was performed using 123 microsatellite loci. This resulted in the identification of 15 linkage groups/subgroups that formed a first-generation condor genetic map, while no markers linked to a lethal chondrodystrophy mutation were found. A panel of polymorphic markers that is instrumental in molecular parentage diagnostics and other genetic studies in the California condor was selected. Further condor conservation genomics research will be focused on updating the linkage map and integrating it with cytogenetic and BAC-based physical maps and ultimately with the genome sequence assembly.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Animals (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Animals (Basel) Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza