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Discovery of a small molecule ligand of FRS2 that inhibits invasion and tumor growth.
Santhana Kumar, Karthiga; Brunner, Cyrill; Schuster, Matthias; Kopp, Levi Luca; Gries, Alexandre; Yan, Shen; Jurt, Simon; Moehle, Kerstin; Bruns, Dominique; Grotzer, Michael; Zerbe, Oliver; Schneider, Gisbert; Baumgartner, Martin.
Afiliación
  • Santhana Kumar K; Pediatric Molecular Neuro-Oncology Research Laboratory, Children's Research Center, University Children's Hospital Zürich, Zurich, Switzerland.
  • Brunner C; Invasight, Zurich, Switzerland.
  • Schuster M; ETH Zurich, Department of Chemistry and Applied Biosciences, RETHINK, Zurich, Switzerland.
  • Kopp LL; Department of Chemistry, University of Zurich, Zurich, Switzerland.
  • Gries A; Pediatric Molecular Neuro-Oncology Research Laboratory, Children's Research Center, University Children's Hospital Zürich, Zurich, Switzerland.
  • Yan S; Pediatric Molecular Neuro-Oncology Research Laboratory, Children's Research Center, University Children's Hospital Zürich, Zurich, Switzerland.
  • Jurt S; Pediatric Molecular Neuro-Oncology Research Laboratory, Children's Research Center, University Children's Hospital Zürich, Zurich, Switzerland.
  • Moehle K; Department of Chemistry, University of Zurich, Zurich, Switzerland.
  • Bruns D; Department of Chemistry, University of Zurich, Zurich, Switzerland.
  • Grotzer M; ETH Zurich, Department of Chemistry and Applied Biosciences, RETHINK, Zurich, Switzerland.
  • Zerbe O; Department of Oncology, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland.
  • Schneider G; Department of Chemistry, University of Zurich, Zurich, Switzerland.
  • Baumgartner M; ETH Zurich, Department of Chemistry and Applied Biosciences, RETHINK, Zurich, Switzerland.
Cell Oncol (Dordr) ; 46(2): 331-356, 2023 Apr.
Article en En | MEDLINE | ID: mdl-36495366
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Descubrimiento de Drogas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cell Oncol (Dordr) Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Descubrimiento de Drogas Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Cell Oncol (Dordr) Año: 2023 Tipo del documento: Article País de afiliación: Suiza Pais de publicación: Países Bajos