Biofabrication of Modular Spheroids as Tumor-Scale Microenvironments for Drug Screening.

Mekhileri, Naveen Vijayan; Major, Gretel; Lim, Khoon; Mutreja, Isha; Chitcholtan, Kenny; Phillips, Elisabeth; Hooper, Gary; Woodfield, Tim

Mekhileri, Naveen Vijayan; Major, Gretel; Lim, Khoon; Mutreja, Isha; Chitcholtan, Kenny; Phillips, Elisabeth; Hooper, Gary; Woodfield, Tim.

Afiliación

Mekhileri NV; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Major G; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Lim K; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Mutreja I; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Chitcholtan K; Department of Obstetrics and Gynaecology, Gynaecological Cancer Research Group, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Phillips E; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Hooper G; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.
Woodfield T; Department of Orthopaedic Surgery and Musculoskeletal Medicine, Centre for Bioengineering & Nanomedicine, University of Otago, Christchurch, Canterbury, 8011, New Zealand.

Adv Healthc Mater ; 12(14): e2201581, 2023 06.

Article en En | MEDLINE | ID: mdl-36495232

Asunto(s)

Esferoides Celulares; Microambiente Tumoral; Evaluación Preclínica de Medicamentos; Reproducibilidad de los Resultados; Técnicas de Cocultivo

Palabras clave

drug screening; microspheres; modular assembly; spheroids; tumor microenvironment; tumor-scale models

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esferoides Celulares / Microambiente Tumoral Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Adv Healthc Mater Año: 2023 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Alemania

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