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Assessment of Disease Severity and Quality of Life in Patients with Atopic Dermatitis from South Korea.
Son, Sang Wook; Lee, Ji Hyun; Ahn, Jiyoung; Chang, Sung Eun; Choi, Eung Ho; Han, Tae Young; Jang, Yong Hyun; Kim, Hye One; Kim, Moon-Bum; Kim, You Chan; Ko, Hyun Chang; Ko, Joo Yeon; Lee, Sang Eun; Lee, Yang Won; Lew, Bark-Lynn; Na, Chan Ho; Park, Chang Ook; Park, Chun Wook; Park, Kui Young; Park, Kun; Park, Young Lip; Roh, Joo Young; Seo, Young-Joon; Shin, Min Kyung; Lee, Sujin; Cho, Sang Hyun.
Afiliación
  • Son SW; Department of Dermatology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
  • Lee JH; Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
  • Ahn J; Department of Dermatology, National Medical Center, Seoul, Korea.
  • Chang SE; Department of Dermatology and Research Institute of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
  • Choi EH; Department of Dermatology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • Han TY; Department of Dermatology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.
  • Jang YH; Department of Dermatology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.
  • Kim HO; Department of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.
  • Kim MB; Department of Dermatology, Pusan National University Hospital, Busan, Korea.
  • Kim YC; Department of Dermatology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.
  • Ko HC; Department of Dermatology, Pusan National University Yangsan Hospital, School of Medicine, Pusan National University, Yangsan, Korea.
  • Ko JY; Department of Dermatology, Hanyang University Seoul Hospital, Hanyang University College of Medicine, Seoul, Korea.
  • Lee SE; Department of Dermatology and Cutaneous Biology Research Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • Lee YW; Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
  • Lew BL; Department of Dermatology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea.
  • Na CH; Department of Dermatology, Chosun University Hospital, College of Medicine, Chosun University, Gwangju, Korea.
  • Park CO; Department of Dermatology and Cutaneous Biology Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
  • Park CW; Department of Dermatology, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea.
  • Park KY; Department of Dermatology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
  • Park K; Department of Dermatology, Wonkwang University Hospital, Iksan, Korea.
  • Park YL; Department of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.
  • Roh JY; Department of Dermatology, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.
  • Seo YJ; Department of Dermatology, Chungnam National University Hospital, Daejeon, Korea.
  • Shin MK; Department of Dermatology, Kyung Hee University Hospital, College of Medicine, Kyung Hee University, Seoul, Korea.
  • Lee S; Medical Affairs, Sanofi-Aventis Korea Co., Ltd., Seoul, Korea.
  • Cho SH; Department of Dermatology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. drchosh@hotmail.com.
Ann Dermatol ; 34(6): 419-430, 2022 Dec.
Article en En | MEDLINE | ID: mdl-36478424
BACKGROUND: Data illustrating the impact of atopic dermatitis (AD) on lives of adults with AD in South Korea are limited. OBJECTIVE: To assess the AD disease severity and its impact on quality of life (QoL) in patients with AD from South Korea. METHODS: Patients with AD utilizing the specialist dermatology services of major hospitals in South Korea were assessed for disease severity using Eczema Area and Severity Index (EASI) score, for QoL using Dermatology Life Quality Index (DLQI) (for QoL), and for comorbidities and treatment experience via retrospective review of 12-month medical records. Clinical and sociodemographic characteristics were also measured. RESULTS: Of the 1,163 patients, 695 (59.8%) were men (mean age [years]±standard deviation: 31.6±12.1). Overall, 52.9% (n=615) patients had moderate-to-severe disease (EASI>7). The QoL of 72.3% (n=840) patients was affected moderately-to-severely (DLQI score: 6~30). Systemic immunosuppressants were used ≥1 over past 12 months in 51.9% (n=603) patients, and the most commonly used were cyclosporines (45.7%, n=531) and systemic corticosteroids (40.5%, n=471). Approximately, 10.8% (n=126) patients consulted or received treatment for AD-related eye problem. Of these, 40% (n=50) patients reported poor, very poor, or completely blind status; approximately, 16.7% patients (n=192) reported having depression or anxiety; and 35.5% (n=410) reported suicidal ideation or suicidal attempt. CONCLUSION: A large proportion of patients had moderate-to-severe AD, a compromised QoL, and ocular or mental health comorbidities, indicating a high disease burden despite systemic treatment. These findings highlight the importance of a holistic approach for the evaluation and treatment of patients with AD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Ann Dermatol Año: 2022 Tipo del documento: Article Pais de publicación: Corea del Sur
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Ann Dermatol Año: 2022 Tipo del documento: Article Pais de publicación: Corea del Sur