Your browser doesn't support javascript.
loading
Reliability and concurrent validity of three-dimensional ultrasound for quantifying knee cartilage volume.
Papernick, S; Dima, R; Gillies, D J; Appleton, C T; Fenster, A.
Afiliación
  • Papernick S; Department of Medical Biophysics, Western University Canada, London, Ontario, Canada.
  • Dima R; Robarts Research Institute, Western University Canada, London, Ontario, Canada.
  • Gillies DJ; Department of Health and Rehabilitation Sciences; Western University Canada, London, Ontario, Canada.
  • Appleton CT; Department of Medical Biophysics, Western University Canada, London, Ontario, Canada.
  • Fenster A; Robarts Research Institute, Western University Canada, London, Ontario, Canada.
Osteoarthr Cartil Open ; 2(4): 100127, 2020 Dec.
Article en En | MEDLINE | ID: mdl-36474884
Objective: The goal of this study was to test the reliability and validity of a handheld mechanical three-dimensional (3D) ultrasound (US) device for quantifying femoral articular cartilage (FAC) against the current clinical standard of magnetic resonance imaging (MRI). Design: Bilateral knee images of 25 healthy volunteers were acquired with 3D US and 3.0 T MRI. The trochlear FAC was segmented by two raters who repeated segmentations on five cases during separate sessions. MRI and 3D US segmentations were registered using a semi-automated surface-based registration algorithm, and MRI segmentations were trimmed to match the FAC region from 3D US. Intra- (n = 5) and inter-rater (n = 25) reliabilities were assessed using intraclass correlation coefficients (ICCs) calculated from FAC volumes. Relationships between MRI and 3D US were assessed using Spearman correlation and linear regression (n = 25). Results: MRI intra-rater ICCs were 0.97 (0.79, 1.00) and 0.90 (0.25, 0.99) for each rater with an inter-rater ICC of 0.83 (0.48, 0.94). 3D US intra-rater ICCs were 1.00 (0.98, 1.00) and 0.98 (0.84, 1.00) for each rater with an inter-rater ICC of 0.96 (0.90, 0.98). Spearman correlation and linear regression revealed a strong correlation ρ = 0.884 (0.746, 0.949) and regression R2 = 0.848 (0.750, 0.950). Conclusion: These results suggest 3D US demonstrates excellent intra- and inter-rater reliabilities and strong concurrent validity with MRI when quantifying healthy trochlear FAC volume. 3D US may reduce imaging costs and greatly improve feasibility of quantifying knee cartilage volume during knee arthritis clinical trials and patient care.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Osteoarthr Cartil Open Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Osteoarthr Cartil Open Año: 2020 Tipo del documento: Article País de afiliación: Canadá Pais de publicación: Reino Unido