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CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.
Jutzi, Jonas S; Marneth, Anna E; Jiménez-Santos, María José; Hem, Jessica; Guerra-Moreno, Angel; Rolles, Benjamin; Bhatt, Shruti; Myers, Samuel A; Carr, Steven A; Hong, Yuning; Pozdnyakova, Olga; van Galen, Peter; Al-Shahrour, Fátima; Nam, Anna S; Mullally, Ann.
Afiliación
  • Jutzi JS; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Marneth AE; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Jiménez-Santos MJ; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
  • Hem J; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Guerra-Moreno A; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Rolles B; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Bhatt S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Myers SA; Department of Pharmacy, National University of Singapore, Singapore, Singapore.
  • Carr SA; Center for Autoimmunity and Inflammation, La Jolla Institute for Immunology, La Jolla, CA, 92037, USA.
  • Hong Y; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Pozdnyakova O; Department of Chemistry and Physics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, 3083, Australia.
  • van Galen P; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Al-Shahrour F; Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Nam AS; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Mullally A; Bioinformatics Unit, Structural Biology Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.
Leukemia ; 37(2): 359-369, 2023 02.
Article en En | MEDLINE | ID: mdl-36473980
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calreticulina / Complejo de la Endopetidasa Proteasomal / Estrés del Retículo Endoplásmico Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calreticulina / Complejo de la Endopetidasa Proteasomal / Estrés del Retículo Endoplásmico Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido