Co-exposure to aflatoxin B1 and therapeutic coartem worsens hepatic and renal function through enhanced oxido-inflammatory responses and apoptosis in rats.

Owumi, Solomon E; Otunla, Moses T; Elerewe, Oyindamola O; Arunsi, Uche O

Owumi, Solomon E; Otunla, Moses T; Elerewe, Oyindamola O; Arunsi, Uche O.

Afiliación

Owumi SE; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200004, Nigeria. Electronic address: zicri@hotmail.com.
Otunla MT; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200004, Nigeria.
Elerewe OO; Cancer Research and Molecular Biology Laboratories, Department of Biochemistry, Faculty of Basic Medical Sciences, University of Ibadan, 200004, Nigeria.
Arunsi UO; Department of Cancer Immunology and Biotechnology, School of Medicine, University of Nottingham, Nottingham, NG7 2RD, UK.

Toxicon ; 222: 106988, 2023 Jan 15.

Article en En | MEDLINE | ID: mdl-36473514

Asunto(s)

Aflatoxina B1; Antioxidantes; Animales; Ratas; Antioxidantes/farmacología; Aflatoxina B1/toxicidad; Aflatoxina B1/metabolismo; Combinación Arteméter y Lumefantrina/metabolismo; Combinación Arteméter y Lumefantrina/farmacología; Estrés Oxidativo; Ratas Wistar; Hígado; Apoptosis; Riñón/metabolismo

Palabras clave

Aflatoxin; Apoptosis; Coartem; Hepatorenal toxicity; Oxido-inflammatory stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aflatoxina B1 / Antioxidantes Límite: Animals Idioma: En Revista: Toxicon Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido

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