Fisetin reduces the senescent tubular epithelial cell burden and also inhibits proliferative fibroblasts in murine lupus nephritis.

Ijima, Shogo; Saito, Yuki; Nagaoka, Kentaro; Yamamoto, Sena; Sato, Tsukasa; Miura, Norihiro; Iwamoto, Taiki; Miyajima, Maki; Chikenji, Takako S

Ijima, Shogo; Saito, Yuki; Nagaoka, Kentaro; Yamamoto, Sena; Sato, Tsukasa; Miura, Norihiro; Iwamoto, Taiki; Miyajima, Maki; Chikenji, Takako S.

Afiliación

Ijima S; Department of Oral Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
Saito Y; Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan.
Nagaoka K; Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan.
Yamamoto S; Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan.
Sato T; Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan.
Miura N; Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan.
Iwamoto T; Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan.
Miyajima M; Graduate School of Health Sciences, Hokkaido University, Sapporo, Japan.
Chikenji TS; Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan.

Front Immunol ; 13: 960601, 2022.

Article en En | MEDLINE | ID: mdl-36466895

Asunto(s)

Lupus Eritematoso Sistémico; Nefritis Lúpica; Ratones; Animales; Ratones Endogámicos MRL lpr; Nefritis Lúpica/tratamiento farmacológico; Fibroblastos; Células Epiteliales; Factor de Crecimiento Transformador beta; Antioxidantes

Palabras clave

fisetin; lupus nephritis (LN); p15INK4B; senescence; senolytic agent; systemic lupus erythematosus (SLE); transforming growth factor ß (TGF-ß)

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Nefritis Lúpica / Lupus Eritematoso Sistémico Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google