An intranasal vaccine targeting the receptor binding domain of SARS-CoV-2 elicits a protective immune response.

Chen, Li; Zhang, Haiwei; Li, Moxuan; Wu, Bihao; Zhang, Zhe; Gong, Rui

Chen, Li; Zhang, Haiwei; Li, Moxuan; Wu, Bihao; Zhang, Zhe; Gong, Rui.

Afiliación

Chen L; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
Zhang H; University of Chinese Academy of Sciences, Beijing, China.
Li M; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
Wu B; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.
Zhang Z; University of Chinese Academy of Sciences, Beijing, China.
Gong R; CAS Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China.

Front Immunol ; 13: 1005321, 2022.

Article en En | MEDLINE | ID: mdl-36466882

Asunto(s)

COVID-19; Vacunas; Animales; Ratones; SARS-CoV-2; COVID-19/prevención & control; Inmunidad Mucosa

Palabras clave

RBD-Fc; SARS-CoV-2; intranasal vaccine; mucosal immunity; mucosal vaccine

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vacunas / COVID-19 Límite: Animals Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Suiza

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