Transaminase-mediated chiral selective synthesis of (1R)-(3-methylphenyl)ethan-1-amine from 1-(3-methylphenyl)ethan-1-one: process minutiae, optimization, characterization and 'What If studies'.

Khatik, Amol Gulab; Muley, Abhijeet Bhimrao; More, Pavankumar Ramdas; Jain, Arvind Kumar

Khatik, Amol Gulab; Muley, Abhijeet Bhimrao; More, Pavankumar Ramdas; Jain, Arvind Kumar.

Afiliación

Khatik AG; School of Basic & Applied Sciences, Galgotias University, Gautam Buddh Nagar, Greater Noida, Uttar Pradesh, 201310, India. amol.khatik@gmail.com.
Muley AB; Research and Development, Cherish Pharma, Nashik, Maharashtra, 22010, India. abhijeetmuleypatil@gmail.com.
More PR; Research and Development, Cherish Pharma, Nashik, Maharashtra, 22010, India.
Jain AK; School of Basic & Applied Sciences, Galgotias University, Gautam Buddh Nagar, Greater Noida, Uttar Pradesh, 201310, India.

Bioprocess Biosyst Eng ; 46(2): 207-225, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36463332

Asunto(s)

Aminas; Transaminasas; Aminas/química; Transaminasas/química; Estereoisomerismo; Biocatálisis; Temperatura

Palabras clave

(1R)-(3-methylphenyl)ethan-1-amine; 1-(3-methylphenyl)ethan-1-one; Chiral selective synthesis; Process optimization and development; Transaminases (ATA-025); Transamination

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aminas / Transaminasas Idioma: En Revista: Bioprocess Biosyst Eng Asunto de la revista: BIOTECNOLOGIA / ENGENHARIA BIOMEDICA Año: 2023 Tipo del documento: Article País de afiliación: India Pais de publicación: Alemania

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