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Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease.
Zephyr, Jacqueto; Rao, Desaboini Nageswara; Johnson, Colby; Shaqra, Ala M; Nalivaika, Ellen A; Jordan, Aria; Kurt Yilmaz, Nese; Ali, Akbar; Schiffer, Celia A.
Afiliación
  • Zephyr J; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Rao DN; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Johnson C; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Shaqra AM; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Nalivaika EA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Jordan A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States.
  • Kurt Yilmaz N; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States. Electronic address: Nese.KurtYilmaz@umassmed.edu.
  • Ali A; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States. Electronic address: Akbar.Ali@umassmed.edu.
  • Schiffer CA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, United States. Electronic address: Celia.Schiffer@umassmed.edu.
Bioorg Chem ; 131: 106269, 2023 02.
Article en En | MEDLINE | ID: mdl-36446201
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavivirus / Virus Zika / Infección por el Virus Zika Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Flavivirus / Virus Zika / Infección por el Virus Zika Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos