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The Effect of Temperament on the Association Between Pre-treatment Anxiety and Chemotherapy-Related Symptoms in Patients With Breast Cancer.
Choi, Jung-In; Jung, Sanghyup; Oh, Gyu Han; Son, Kyung-Lak; Lee, Kwang-Min; Jung, Dooyoung; Kim, Tae-Yong; Im, Seock-Ah; Lee, Kyung-Hun; Shin, Min-Sup; Hahm, Bong-Jin; Yeom, Chan-Woo.
Afiliación
  • Choi JI; Department of Clinical Medical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Jung S; Department of Neuropsychiatry, Seoul National University Hospital, Seoul, Republic of Korea.
  • Oh GH; Department of Psychiatry, National Rehabilitation Center, Seoul, Republic of Korea.
  • Son KL; Department of Psychiatry and Behavioral Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea.
  • Lee KM; Public Health Medical Service, Seoul National University Hospital, Seoul, Republic of Korea.
  • Jung D; Department of Psychiatry, Dongguk University Ilsan Hospital, Goyang, Republic of Korea.
  • Kim TY; Mind Lab the Place, Seoul, Republic of Korea.
  • Im SA; Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
  • Lee KH; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  • Shin MS; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
  • Hahm BJ; Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
  • Yeom CW; Cancer Research Institute, Seoul National University, Seoul, Republic of Korea.
Psychiatry Investig ; 19(11): 949-957, 2022 Nov.
Article en En | MEDLINE | ID: mdl-36444158
OBJECTIVE: Pre-treatment anxiety (PA) before chemotherapy increases complaints of chemotherapy-related symptoms (CRS). The results on the association have been inconsistent, and the effect of temperament remains unclear. We aimed to determine whether PA is a risk factor for CRS and the effect of differing temperaments on CRS. METHODS: This prospective study comprised 176 breast cancer patients awaiting adjuvant chemotherapy post-surgery. We assessed CRS, PA, and temperament using the MD Anderson Symptom Inventory (MDASI), the Hospital Anxiety and Depression Scale, and the short form of the Temperament and Character Inventory-Revised, respectively. The MDASI was re-administered three weeks after the first chemo-cycle. RESULTS: PA showed weak positive correlation with several CRS after the first cycle; no CRS was significantly associated with PA when pre-treatment depressive symptoms and baseline CRS were adjusted in multiple regression analysis. Moderation model analysis indicated that the PA effect on several CRS, including pain, insomnia, anorexia, dry mouth, and vomiting, was moderated by harm avoidance (HA) but not by other temperament dimensions. In particular, PA was positively associated with CRS in patients with low HA. CONCLUSION: The results in patients with low HA indicate that more attention to PA in patients with confident and optimistic temperaments is necessary.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Psychiatry Investig Año: 2022 Tipo del documento: Article Pais de publicación: Corea del Sur

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: Psychiatry Investig Año: 2022 Tipo del documento: Article Pais de publicación: Corea del Sur