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[Latest Findings on Prediction and Prevention of Preeclampsia].
Ye, Yun-Zhen; Zhou, Qiong-Jie; Xiao, Xi-Rong; Xiong, Yu; Li, Xiao-Tian.
Afiliación
  • Ye YZ; Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
  • Zhou QJ; Shanghai Institute of Reproductive Endocrinology, Shanghai 200011, China.
  • Xiao XR; Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
  • Xiong Y; Shanghai Institute of Reproductive Endocrinology, Shanghai 200011, China.
  • Li XT; Obstetrics and Gynecology Hospital of Fudan University, Shanghai 200011, China.
Sichuan Da Xue Xue Bao Yi Xue Ban ; 53(6): 1012-1015, 2022 Nov.
Article en Zh | MEDLINE | ID: mdl-36443044
Preeclampsia, a progressive disease involving multiple systems, afflicts pregnancy specifically. It contributes to severe maternal and perinatal morbidity and mortality. It has been reported that preeclampsia initiates from a mismatch between the utero-placental supply and demand, which subsequently triggers the release of placental syncytiotrophoblast stress-derived factors and an imbalance of proangiogenic/antiangiogenic factors, eventually causing maternal systemic endothelial lesions and systemic inflammatory response. Currently, treatments available for preeclampsia are very limited in number. Hence, prediction and prevention carry special significance. Herein, we reviewed the current understanding of preeclampsia, especially findings on the prediction and prevention of preeclampsia published within the past 5 years. We discussed the Fetal Medicine Foundation (FMF) screening model based on placental growth factor (PlGF) and the effects of aspirin, calcium, exercise, and termination of pregnancy in preventing preeclampsia. The efficacy and safety of other new preventive measures still need further validation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Pregnancy Idioma: Zh Revista: Sichuan Da Xue Xue Bao Yi Xue Ban Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Pregnancy Idioma: Zh Revista: Sichuan Da Xue Xue Bao Yi Xue Ban Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: China