Availability of aldo-keto reductase 1C3 and ATP-binding cassette B1 as therapeutic targets for alleviating paclitaxel resistance in breast cancer MCF7 cells.

Matsunaga, Toshiyuki; Horinouchi, Misato; Saito, Haruhi; Hisamatsu, Aki; Iguchi, Kazuhiro; Yoshino, Yuta; Endo, Satoshi; Ikari, Akira

Matsunaga, Toshiyuki; Horinouchi, Misato; Saito, Haruhi; Hisamatsu, Aki; Iguchi, Kazuhiro; Yoshino, Yuta; Endo, Satoshi; Ikari, Akira.

Afiliación

Matsunaga T; Laboratory of Bioinformatics, Gifu Pharmaceutical University, 5-6-1 Mitahora-higashi, Gifu 502-8585, Japan.
Horinouchi M; Education Center of Pharmaceutical Sciences, Gifu Pharmaceutical University, 5-6-1 Mitahora-higashi, Gifu 502-8585, Japan.
Saito H; Laboratory of Biochemistry, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Hisamatsu A; Laboratory of Biochemistry, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Iguchi K; Education Center of Pharmaceutical Sciences, Gifu Pharmaceutical University, 5-6-1 Mitahora-higashi, Gifu 502-8585, Japan.
Yoshino Y; Laboratory of Community Pharmacy, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Endo S; Laboratory of Biochemistry, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.
Ikari A; Laboratory of Biochemistry, Gifu Pharmaceutical University, 1-25-4 Daigaku-nishi, Gifu 501-1196, Japan.

J Biochem ; 173(3): 167-175, 2023 Mar 07.

Article en En | MEDLINE | ID: mdl-36413758

Asunto(s)

Neoplasias; Paclitaxel; Humanos; Adenosina Trifosfato; Aldehídos; Células MCF-7; Paclitaxel/farmacología

Palabras clave

ATP-binding cassette B1; Aldo-keto reductase 1C3 Abbreviations: AKR, aldo-keto reductase; BPS, 3-bromo-5-phenylsalicylic acid; BSO, buthionine sulfoximine; CDDP, cis-diamminedichloroplatinum; CDDP-R, CDDP-resistant MCF7; DPBS, Dulbecco's phosphate-buffered saline; DTNB, 5,5'-dithiobis(2-nitrobenzoic acid); DTX, docetaxel; GCL, glutamate-cysteine ligase; GPx, glutathione peroxidase; GR, glutathione reductase; GSH, reduced glutathione; GSHEE, glutathione ethyl ester; GST, glutathione S-transferase; HNE, 4-hydroxy-2-nonenal; Keap1, Kelch-like ECH associated protein 1; MCA, 4-methylcoumaryl-7-amide; MG132, Z-Leu-Leu-Leu-al; Nrf2, nuclear factor erythroid 2-related factor 2; PCR, polymerase-chain reaction; PG, prostaglandin; ROS, reactive oxygen species; SFN, sulforaphane; siRNA, small-interfering RNA; TOL, tolfenamic acid; UDCA, ursodeoxycholic acid; breast cancer; chemoresistance; docetaxel; paclitaxel

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Paclitaxel / Neoplasias Límite: Humans Idioma: En Revista: J Biochem Año: 2023 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Reino Unido

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