Neuroprotective potential of plant derived parenchymal stem cells extract on environmental and genetic models of Parkinson disease through attenuation of oxidative stress and neuroinflammation.

Ishola, I O; Oloyo, A K; Olubodun-Obadun, T G; Godswill, O D; Omilabu, S A; Adeyemi, O O

Ishola, I O; Oloyo, A K; Olubodun-Obadun, T G; Godswill, O D; Omilabu, S A; Adeyemi, O O.

Afiliación

Ishola IO; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria. oishola@cmul.edu.ng.
Oloyo AK; Department of Physiology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria.
Olubodun-Obadun TG; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria.
Godswill OD; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria.
Omilabu SA; Department of Medical Microbiology and Parasitology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria.
Adeyemi OO; Department of Pharmacology, Therapeutics and Toxicology, Faculty of Basic Medical Sciences, College of Medicine, University of Lagos, Lagos, Lagos State, Nigeria.

Metab Brain Dis ; 38(2): 557-571, 2023 Feb.

Article en En | MEDLINE | ID: mdl-36401682

Asunto(s)

Fármacos Neuroprotectores; Enfermedad de Parkinson; Extractos Vegetales; Animales; Ratones; 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina/metabolismo; 1-Metil-4-fenil-1,2,3,6-Tetrahidropiridina/farmacología; alfa-Sinucleína/metabolismo; Antioxidantes/farmacología; Modelos Animales de Enfermedad; Neuronas Dopaminérgicas/metabolismo; Drosophila melanogaster; Ratones Endogámicos C57BL; Modelos Genéticos; Enfermedades Neuroinflamatorias; Fármacos Neuroprotectores/farmacología; Fármacos Neuroprotectores/uso terapéutico; Estrés Oxidativo; Enfermedad de Parkinson/metabolismo; Sustancia Negra/metabolismo; Extractos Vegetales/farmacología

Palabras clave

Double stem cells®; MPTP; Neuroinflammation; Oxidative stress; Parkinson disease; α-synuclein

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Extractos Vegetales / Fármacos Neuroprotectores Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Metab Brain Dis Asunto de la revista: CEREBRO / METABOLISMO Año: 2023 Tipo del documento: Article País de afiliación: Nigeria Pais de publicación: Estados Unidos

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