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Use of Bleach Baths for Atopic Dermatitis: An Indian Perspective.
Sharma, Nidhi; Dhar, Sandipan; De, Abhishek; Godse, Kiran; Shankar, D S Krupa; Zawar, Vijay; Girdhar, Mukesh; Shah, Bela.
Afiliación
  • Sharma N; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Dhar S; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • De A; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Godse K; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Shankar DSK; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Zawar V; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Girdhar M; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
  • Shah B; Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.
Indian J Dermatol ; 67(3): 273-278, 2022.
Article en En | MEDLINE | ID: mdl-36386066
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder affecting 15-20% of children and 1-10% of adults. Staphylococcus aureus (S. aureus) infection is the most frequent complication of AD and is involved in the worsening of the disease. Systemic and topical antibiotics are used in the treatment for AD but there are concerns over increasing resistance. Bleach (sodium hypochlorite, NaOCl) baths are an inexpensive, widely accessible, alternative antibiotic treatment that may not worsen antibiotic resistance. Bleach baths are used as adjunctive treatment in AD patients to treat superinfections, although their mechanism of action is not well understood. Balancing safety concerns with efficacious treatment should be important especially for AD where the majority of patients are in pediatrics age groups. Studies available in PubMed databases were included in this review. Most suggested bleach bath improves clinical symptoms of AD and restores surface microbiome by eradicating bacteria, most notably S. aureus. Some studies have noted that this antimicrobial effect has reduced the need for topical corticosteroids. In addition, bleach seems to have strong anti-inflammatory and antipruritic effects. Overall, bleach baths seem to be safe on human skin, without disrupting the epidermal barrier function. The review concluded, although there are some advantages of use of bleach baths, more studies to investigate long-term efficacy and safety of bleach baths are required before fixing its role in the treatment of AD especially in the context of the Indian scenario.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Indian J Dermatol Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Systematic_reviews Idioma: En Revista: Indian J Dermatol Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: India