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Design and Structural Optimization of Orally Bioavailable SOS1 Inhibitors for the Treatment of KRAS-Driven Carcinoma.
Zhang, Silong; Zhang, Yu; Chen, Xin; Xu, Juan; Fang, Huaxiang; Li, Yuanyuan; Liu, Yi; He, Huan.
Afiliación
  • Zhang S; Key Laboratory of Coal Conversion and New Carbon Materials of Hubei Province, College of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan430081, P. R. China.
  • Zhang Y; Wuhan Yuxiang Pharmaceutial Technology Co., Ltd., Wuhan430200, P. R. China.
  • Chen X; Key Laboratory of Coal Conversion and New Carbon Materials of Hubei Province, College of Chemistry and Chemical Engineering, Wuhan University of Science and Technology, Wuhan430081, P. R. China.
  • Xu J; School of Life Science and Technology & School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan430023, P. R. China.
  • Fang H; Wuhan Yuxiang Pharmaceutial Technology Co., Ltd., Wuhan430200, P. R. China.
  • Li Y; College of Chemistry and Chemical Engineering, Hubei Polytechnic University, Huangshi435003, P. R. China.
  • Liu Y; Wuhan Yuxiang Pharmaceutial Technology Co., Ltd., Wuhan430200, P. R. China.
  • He H; School of Life Science and Technology & School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan430023, P. R. China.
J Med Chem ; 65(23): 15856-15877, 2022 12 08.
Article en En | MEDLINE | ID: mdl-36384290
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma / Proteína SOS1 Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Carcinoma / Proteína SOS1 Límite: Animals / Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos