Your browser doesn't support javascript.
loading
Psychiatric healthcare resource utilization following initiation of aripiprazole once-monthly: a retrospective real-world study.
Waters, Heidi C; Touya, Maelys; Wee, Soon Nan; Ng, Michelle; Thadani, Simran; Surendran, Subina; Rentería, Miguel; Rush, A John; Patel, Rashmi; Sarkar, Joydeep; Fitzgerald, Heather M; Han, Xue.
Afiliación
  • Waters HC; Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, NJ, USA.
  • Touya M; Lundbeck, Deerfield, IL, USA.
  • Wee SN; Holmusk Technologies Inc, New York, NY, USA.
  • Ng M; Holmusk Technologies Inc, New York, NY, USA.
  • Thadani S; Holmusk Technologies Inc, New York, NY, USA.
  • Surendran S; Holmusk Technologies Inc, New York, NY, USA.
  • Rentería M; Holmusk Technologies Inc, New York, NY, USA.
  • Rush AJ; Department of Psychiatry, Duke-National University of Singapore (NUS), Singapore.
  • Patel R; Duke University School of Medicine, Durham, NC, USA.
  • Sarkar J; Texas Tech Health Sciences Center, Odessa, TX, USA.
  • Fitzgerald HM; Holmusk Technologies Inc, New York, NY, USA.
  • Han X; King's College London, London, UK.
Curr Med Res Opin ; 39(2): 299-306, 2023 02.
Article en En | MEDLINE | ID: mdl-36380678
OBJECTIVES: This observational retrospective real-world study examined changes in healthcare resource utilization (HCRU) pre- and post-initiation of aripiprazole once-monthly (AOM 400) in patients with schizophrenia or bipolar I disorder. METHODS: Electronic health record-derived, de-identified data from the NeuroBlu Database (2013-2020) were used to identify patients ≥18 years with schizophrenia (n = 222) or bipolar I disorder (n = 129) who were prescribed AOM 400, and had visit data within 3, 6, 9, or 12 months pre- and post-initial AOM 400 prescription. Rates of inpatient hospitalization, emergency department visits, inpatient readmissions, and average length of stay were examined and compared over 3, 6, 9, and 12 months pre-/post-AOM 400 using a McNemar test. RESULTS: Statistically significant differences were seen in both schizophrenia and bipolar I disorder patient cohorts pre- and post-AOM 400 in inpatient hospitalization rates (p < .001 all time points, both cohorts) and 30-day readmission per patient rates (p < .001 all time points, both cohorts). Statistically significant improvement in mean length of stay was observed in both cohorts at all time points, except for at six months in patients with schizophrenia. Emergency department visit rates were significantly lower after AOM 400 initiation for both cohorts at all time points (p < .001). CONCLUSIONS: A reduction in the rate of hospitalizations, emergency department visits, 30-day readmissions, and average length-of-stay was observed for patients diagnosed with either schizophrenia or bipolar I disorder, which suggests a positive effect of AOM 400 treatment on HCRU outcomes and is supportive of earlier analyses from different data sources.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos Aspecto: Implementation_research Límite: Humans Idioma: En Revista: Curr Med Res Opin Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esquizofrenia / Antipsicóticos Aspecto: Implementation_research Límite: Humans Idioma: En Revista: Curr Med Res Opin Año: 2023 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido