Roux-en-Y reconstruction alleviates radical gastrectomy-induced colitis via down-regulation of the butyrate/NLRP3 signaling pathway.

Yao, Yizhou; Sun, Shishuo; Gu, Jinrong; Ni, Haishun; Zhong, Kaiqiang; Xu, Qixuan; Zhou, Diyuan; Wang, Xuchao; Gao, Ling; Zhu, Xinguo

Yao, Yizhou; Sun, Shishuo; Gu, Jinrong; Ni, Haishun; Zhong, Kaiqiang; Xu, Qixuan; Zhou, Diyuan; Wang, Xuchao; Gao, Ling; Zhu, Xinguo.

Afiliación

Yao Y; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Sun S; Cancer Institute, The First Clinical Medical College, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Gu J; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Ni H; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Zhong K; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Xu Q; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Zhou D; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Wang X; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Gao L; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Zhu X; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. Electronic address: xgzhu@suda.edu.cn.

EBioMedicine ; 86: 104347, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36371983

Asunto(s)

Anastomosis en-Y de Roux; Colitis; Gastrectomía; Animales; Ratones; Butiratos/metabolismo; Colitis/etiología; Colitis/metabolismo; Diabetes Mellitus Tipo 2/cirugía; Regulación hacia Abajo; Gastrectomía/efectos adversos; Gastrectomía/métodos; Inflamasomas; Inflamación; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; ARN Ribosómico 16S; Transducción de Señal; Neoplasias Gástricas/cirugía; Resultado del Tratamiento; Anastomosis en-Y de Roux/métodos; Anastomosis en-Y de Roux/veterinaria

Palabras clave

Butyrate; Gut microbiota; NLRP3 inflammasome; Radical gastrectomy; Roux-en-Y reconstruction

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Anastomosis en-Y de Roux / Colitis / Gastrectomía Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EBioMedicine Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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