GBP5 exacerbates rosacea-like skin inflammation by skewing macrophage polarization towards M1 phenotype through the NF-&#954;B signalling pathway.

Zhou, Lei; Zhao, Han; Zhao, He; Meng, Xin; Zhao, Zhixiang; Xie, Hongfu; Li, Ji; Tang, Yan; Zhang, Yiya

GBP5 exacerbates rosacea-like skin inflammation by skewing macrophage polarization towards M1 phenotype through the NF-κB signalling pathway.

Zhou, Lei; Zhao, Han; Zhao, He; Meng, Xin; Zhao, Zhixiang; Xie, Hongfu; Li, Ji; Tang, Yan; Zhang, Yiya.

Afiliación

Zhou L; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Zhao H; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, China.
Zhao H; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Meng X; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Zhao Z; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, China.
Xie H; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Li J; Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.
Tang Y; Hunan Key Laboratory of Aging Biology, Xiangya Hospital, Central South University, Changsha, China.
Zhang Y; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

J Eur Acad Dermatol Venereol ; 37(4): 796-809, 2023 Apr.

Article en En | MEDLINE | ID: mdl-36367676

Asunto(s)

Proteínas de Unión al GTP; FN-kappa B; Rosácea; Animales; Ratones; Dermatitis/genética; Dermatitis/metabolismo; Proteínas de Unión al GTP/genética; Proteínas de Unión al GTP/metabolismo; Inflamación; Macrófagos/metabolismo; FN-kappa B/metabolismo; Fenotipo; ARN Interferente Pequeño; Rosácea/genética; Rosácea/metabolismo

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: FN-kappa B / Rosácea / Proteínas de Unión al GTP Límite: Animals Idioma: En Revista: J Eur Acad Dermatol Venereol Asunto de la revista: DERMATOLOGIA / DOENCAS SEXUALMENTE TRANSMISSIVEIS Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

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