Novel antioxidant peptides from MFGM protein Hydrolysates: Separation, identification and effects on Dexamethasone-induced mitochondrial dysfunction.

Li, He; Guan, Kaifang; Liu, Min; Liu, Dandan; Wang, Wenqiong; Zhu, Aihua

Li, He; Guan, Kaifang; Liu, Min; Liu, Dandan; Wang, Wenqiong; Zhu, Aihua.

Afiliación

Li H; Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China. Electronic address: lhe400080@sina.com.
Guan K; Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China; School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150090, Heilong
Liu M; School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530008, Guangxi, China.
Liu D; Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China.
Wang W; College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, Jiangsu, China.
Zhu A; Jiangsu Engineering Research Center of Cardiovascular Drugs Targeting Endothelial Cells, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, Xuzhou 221116, Jiangsu, China. Electronic address: ahzhu@jsnu.edu.cn.

Food Chem ; 403: 134473, 2023 Mar 01.

Article en En | MEDLINE | ID: mdl-36358083

Asunto(s)

Antioxidantes; Hidrolisados de Proteína; Antioxidantes/farmacología; Antioxidantes/metabolismo; Hidrolisados de Proteína/farmacología; Hidrolisados de Proteína/metabolismo; Cromatografía Liquida; Simulación del Acoplamiento Molecular; Espectrometría de Masas en Tándem; Glucolípidos/química; Proteínas de la Leche/metabolismo; Gotas Lipídicas/metabolismo; Mitocondrias/metabolismo; Dexametasona/farmacología

Palabras clave

Antioxidant activity; MFGM peptide; Mitochondrial function; Molecular docking; Sirt-1/PGC-1α signaling pathway

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Hidrolisados de Proteína / Antioxidantes Idioma: En Revista: Food Chem Año: 2023 Tipo del documento: Article Pais de publicación: Reino Unido

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