Hepatoprotective Effects of <i>Aureobasidium pullulans</i> Derived ß 1,3-1,6 Glucans in a Murine Model of Non-alcoholic Steatohepatitis.

Ikewaki, Nobunao; Levy, Gary A; Kurosawa, Gene; Iwasaki, Masaru; Dedeepiya, Vidyasagar D; Vaddi, Suryaprakash; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K

Hepatoprotective Effects of Aureobasidium pullulans Derived ß 1,3-1,6 Glucans in a Murine Model of Non-alcoholic Steatohepatitis.

Ikewaki, Nobunao; Levy, Gary A; Kurosawa, Gene; Iwasaki, Masaru; Dedeepiya, Vidyasagar D; Vaddi, Suryaprakash; Senthilkumar, Rajappa; Preethy, Senthilkumar; Abraham, Samuel J K.

Afiliación

Ikewaki N; Department of Medical Life Science, Kyushu University of Health and Welfare, Japan.
Levy GA; Institute of Immunology, Junsei Educational Institute, Nobeoka, Miyazaki, Japan.
Kurosawa G; Medicine and Immunology, University of Toronto, Ontario, Canada.
Iwasaki M; Department of Academic Research Support Promotion Facility, Center for Research Promotion and Support, Fujita Health University, Aichi, Japan.
Dedeepiya VD; MabGenesis KK, Nagoya, Japan.
Vaddi S; Centre for Advancing Clinical Research (CACR), University of Yamanashi - School of Medicine, Chuo, Japan.
Senthilkumar R; Mary-Yoshio Translational Hexagon (MYTH), Nichi-In Centre for Regenerative Medicine (NCRM), Chennai, India.
Preethy S; Department of Urology, Yashoda Hospitals, Hyderabad, India.
Abraham SJK; Fujio-Eiji Academic Terrain (FEAT), Nichi-In Centre for Regenerative Medicine (NCRM), Chennai, India.

J Clin Exp Hepatol ; 12(6): 1428-1437, 2022.

Article en En | MEDLINE | ID: mdl-36340302

Palabras clave

ALT, Alanine aminotransferase; ARRIVE, Animal Research: Reporting of In Vivo Experiments; IL, Interleukin; MCP-1, Monocyte chemoattractant protein-1; NAFLD, Non-alcoholic fatty liver disease; NAS, NAFLD Activity Score; NASH, Non-alcoholic steatohepatitis; PPAR, Peroxisome proliferator-activated receptor; STAM, Stelic Animal Model; TGF-ß, Transforming growth factor beta; TIMPs, Tissue inhibitors of matrix metalloproteinases; TNF-α, Tumor necrosis factor alpha; anti-fibrotic; anti-inflammatory; beta-glucans; hepatoprotective; non-alcoholic fatty liver disease (NAFLD); non-alcoholic steatohepatitis (NASH); telmisartan; αSMA, Smooth muscle alpha-actin

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: J Clin Exp Hepatol Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: India

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