[Hydroxynitone suppresses hepatic stellate cell activation by inhibiting TGF-ß1 phosphorylation to alleviate CCl<sub>4</sub>-induced liver fibrosis in rats].

Zhao, Z; Dong, H; Li, B; Shen, B; Guo, Y; Gu, T; Qu, Y; Cai, X; Lu, L

[Hydroxynitone suppresses hepatic stellate cell activation by inhibiting TGF-ß1 phosphorylation to alleviate CCl₄-induced liver fibrosis in rats].

Zhao, Z; Dong, H; Li, B; Shen, B; Guo, Y; Gu, T; Qu, Y; Cai, X; Lu, L.

Afiliación

Zhao Z; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Dong H; Department of Gastroenterology, Taizhou People's hospital, Taizhou 225300, China.
Li B; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Shen B; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Guo Y; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Gu T; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Qu Y; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Cai X; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.
Lu L; Department of Gastroenterology, Shanghai General Hospital of Nanjing Medical University, Shanghai 200080, China.

Nan Fang Yi Ke Da Xue Xue Bao ; 42(10): 1511-1516, 2022 Oct 20.

Article en Zh | MEDLINE | ID: mdl-36329585

Asunto(s)

Células Estrelladas Hepáticas; Factor de Crecimiento Transformador beta1; Animales; Masculino; Ratas; Tetracloruro de Carbono/efectos adversos; Tetracloruro de Carbono/metabolismo; Colágeno Tipo I; Células Estrelladas Hepáticas/metabolismo; Células Estrelladas Hepáticas/patología; Hidroxiprolina/metabolismo; Hidroxiprolina/farmacología; Hidroxiprolina/uso terapéutico; Cirrosis Hepática; Fosforilación; Proteínas Proto-Oncogénicas c-akt/metabolismo; Ratas Sprague-Dawley; Transducción de Señal; Proteínas Smad/metabolismo; Factor de Crecimiento Transformador beta1/metabolismo

Palabras clave

hepatic stellate cells; hydronidone; liver fibrosis; transforming growth factor ß1

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Crecimiento Transformador beta1 / Células Estrelladas Hepáticas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: Zh Revista: Nan Fang Yi Ke Da Xue Xue Bao Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: China

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