Modeling adult COX-2 cerebrospinal fluid pharmacokinetics to inform pediatric investigation.

Hannam, Jacqueline A; Murto, Kimmo T; Anderson, Brian J; Dembo, Gregory; Kharasch, Evan D

Hannam, Jacqueline A; Murto, Kimmo T; Anderson, Brian J; Dembo, Gregory; Kharasch, Evan D.

Afiliación

Hannam JA; Department Pharmacology & Clinical Pharmacology, Faculty Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
Murto KT; Department Anesthesiology and Pain Medicine, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.
Anderson BJ; Department Anaesthesiology, Faculty Medicine and Health Sciences, University of Auckland, Auckland, New Zealand.
Dembo G; Department of Anesthesiology, University of Washington, Seattle, Washington, USA.
Kharasch ED; Department of Anesthesiology and Clinical Chemistry, Duke University School of Medicine, Durham, North Carolina, USA.

Paediatr Anaesth ; 33(4): 291-302, 2023 04.

Article en En | MEDLINE | ID: mdl-36318604

Asunto(s)

Inhibidores de la Ciclooxigenasa 2; Factor de Transferencia; Humanos; Niño; Adulto; Celecoxib; Ciclooxigenasa 2; Antiinflamatorios no Esteroideos

Palabras clave

CSF; analgesia; celecoxib; pharmacokinetics; rofecoxib; valdecoxib

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Factor de Transferencia / Inhibidores de la Ciclooxigenasa 2 Tipo de estudio: Prognostic_studies Límite: Adult / Child / Humans Idioma: En Revista: Paediatr Anaesth Asunto de la revista: ANESTESIOLOGIA / PEDIATRIA Año: 2023 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Francia

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