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Funding has no effect on clinical outcomes of total joint arthroplasty emerging technologies: a systematic review of bibliometrics and conflicts of interest.
Via, Garrhett G; Brueggeman, David A; Lyons, Joseph G; Ely, Isabelle C; Froehle, Andrew W; Krishnamurthy, Anil B.
Afiliación
  • Via GG; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA. ggvia.md@gmail.com.
  • Brueggeman DA; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.
  • Lyons JG; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.
  • Ely IC; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.
  • Froehle AW; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.
  • Krishnamurthy AB; Department of Orthopedic Surgery, Wright State University, 30 E. Apple St., Ste 2200, Dayton, OH, 45409, USA.
Arthroplasty ; 4(1): 45, 2022 Nov 01.
Article en En | MEDLINE | ID: mdl-36316729
BACKGROUND: The use of new total joint arthroplasty technologies, including patient-specific implants/instrumentation (PSI), computer-assisted (CA), and robotic-assisted (RA) techniques, is increasing. There is an ongoing debate regarding the value provided and potential concerns about conflicts of interest (COI). METHODS: PRISMA guidelines were followed. PubMed, MEDLINE, and Web of Science databases were searched for total hip and knee arthroplasties, unicompartmental knee arthroplasties (UKA), PSI, CA, and RA. Bibliometric data, financial COI, clinical/functional scores, and patient-reported outcomes were assessed. RESULTS: Eighty-seven studies were evaluated, with 35 (40.2%) including at least one author reporting COI, and 13 (14.9%) disclosing industry funding. COI and industry funding had no significant effects on outcomes (P = 0.682, P = 0.447), and there were no significant effects of conflicts or funding on level of evidence (P = 0.508, P = 0.826). Studies in which author(s) disclosed COI had significantly higher relative citation ratio (RCR) and impact factor (IF) than those without (P < 0.001, P = 0.032). Subanalysis demonstrated RA and PSI studies were more likely to report COI or industry funding (P = 0.045). RA (OR = 6.31, 95% CI: 1.61-24.68) and UKA (OR = 9.14, 95% CI: 1.43-58.53) had higher odds of reporting favorable outcomes than PSI. CONCLUSIONS: Author COIs (about 40%) may be lower than previously reported in orthopedic technologies/techniques reviews. Studies utilizing RA and PSI were more likely to report COI, while RA and UKA studies were more likely to report favorable outcomes than PSI. No statistically significant association between the presence of COIs and/or industry funding and the frequency of favorable outcomes or study level of evidence was found. LEVEL OF EVIDENCE: Level V Systematic Review.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Systematic_reviews Aspecto: Patient_preference Idioma: En Revista: Arthroplasty Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Guideline / Systematic_reviews Aspecto: Patient_preference Idioma: En Revista: Arthroplasty Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido