Clinical and genetic determinants of the fatty liver-coagulation balance interplay in individuals with metabolic dysfunction.

Valenti, Luca; Tripodi, Armando; La Mura, Vincenzo; Pelusi, Serena; Bianco, Cristiana; Scalambrino, Erica; Margarita, Sara; Malvestiti, Francesco; Ronzoni, Luisa; Clerici, Marigrazia; D'Ambrosio, Roberta; Fraquelli, Mirella; Carpani, Rossana; Prati, Daniele; Peyvandi, Flora

Valenti, Luca; Tripodi, Armando; La Mura, Vincenzo; Pelusi, Serena; Bianco, Cristiana; Scalambrino, Erica; Margarita, Sara; Malvestiti, Francesco; Ronzoni, Luisa; Clerici, Marigrazia; D'Ambrosio, Roberta; Fraquelli, Mirella; Carpani, Rossana; Prati, Daniele; Peyvandi, Flora.

Afiliación

Valenti L; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.
Tripodi A; Università Degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.
La Mura V; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
Pelusi S; Università Degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.
Bianco C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
Scalambrino E; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.
Margarita S; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.
Malvestiti F; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
Ronzoni L; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.
Clerici M; Università Degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.
D'Ambrosio R; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.
Fraquelli M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.
Carpani R; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Gastroenterology and Hepatology, Milan, Italy.
Prati D; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Gastroenterology and Endoscopy, Milan, Italy.
Peyvandi F; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Precision Medicine Lab, Biological Resource Center, Department of Transfusion Medicine, Milan, Italy.

JHEP Rep ; 4(12): 100598, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36313186

Palabras clave

ABO blood group; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CAP, continuous attenuation parameter; CRP, C-reactive protein; F8, factor VIII; FIB-4, Fibrosis-4; FNI, Fibrosis NASH index; FVL, factor V Leiden; GGT, gamma glutamyl transferase; GLM, generalised linear model; HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; LSM, liver stiffness measurement; Liver fibrosis; NAFLD; NAFLD, non-alcoholic fatty liver disease; NASH, non-alcoholic steatohepatitis; PC, protein C; PNPLA3; PRS-5, polygenic risk cosre-5; PRS-HFC, polygenic risk score - hepatic fat content; Pro-C3, N-terminal pro-peptide of collagen-3; vWF, von Willebrand factor; von Willebrand factor

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Prognostic_studies Idioma: En Revista: JHEP Rep Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos

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