Remodeling of the osteoimmune microenvironment after biomaterials implantation in murine tibia: Single-cell transcriptome analysis.

Li, Jia; Zhao, Congrui; Xu, Yangbo; Song, Lu; Chen, Yanqi; Xu, Yuzi; Ma, Yang; Wang, Siyuan; Xu, Antian; He, Fuming

Li, Jia; Zhao, Congrui; Xu, Yangbo; Song, Lu; Chen, Yanqi; Xu, Yuzi; Ma, Yang; Wang, Siyuan; Xu, Antian; He, Fuming.

Afiliación

Li J; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Zhao C; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Xu Y; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Song L; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Chen Y; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Xu Y; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Ma Y; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Wang S; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
Xu A; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.
He F; Department of Prosthodontics, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou, China.

Bioact Mater ; 22: 404-422, 2023 Apr.

Article en En | MEDLINE | ID: mdl-36311047

Palabras clave

BMP2, Bone Morphogenetic Proteins 2; CXCL12, Chemokine (C-X-C mode) Ligand 12; CXCR, CXC Chemokine Receptor; FcgR, Fc Gamma Receptor; IFN-Î³, Interferon-gamma; IL-1ß, Interleukin-1 beta; Implant; MHC, Major Histocompatibility Complex; MIP, Macrophage inflammatory cytokines; MPO, Myeloperoxidase; NE, Neutrophil Elastase; NF-κB, Nuclear Factor Kappa-light-chain-enhancer of Activated B cells; NOD, Nucleotide Binding Oligomerization Domain; Neutrophil; OPG, Osteoprotegerin; Osseointegration; Osteoimmunology; RANKL, Nuclear Factor B receptor Activator Ligand; RUNX2, Runt-related Transcription Factor 2; S100a8, S100 Calcium Binding Protein A8; SDF-1α, Stromal Cell-derived Factor-1 alpha; STAT, Signal Transduction and Transcription Activator; Single-cell transcriptomics; TLR, Toll Like Receptor; TNFα, Tumor Necrosis Factor-alpha; TRAP, Tartrate Resistant Acid Phosphatase

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Bioact Mater Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: China

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google