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Fetal brain biometry and cortical development after maternal SARS-CoV-2 infection in pregnancy: A prospective case-control study.
Mappa, Ilenia; Pietrolucci, Maria Elena; Pavjola, Maqina; Maruotti, Giuseppe; D'Antonio, Francesco; Rizzo, Giuseppe.
Afiliación
  • Mappa I; Department of Obstetrics and Gynecology, Fondazione Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
  • Pietrolucci ME; Department of Obstetrics and Gynecology, Fondazione Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
  • Pavjola M; Department of Obstetrics and Gynecology, Fondazione Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
  • Maruotti G; Department of Obstetrics and Gynecology, University Federico II, Naples, Italy.
  • D'Antonio F; Department of Obstetrics and Gynecology, University di Chieti, Chieti, Italy.
  • Rizzo G; Department of Obstetrics and Gynecology, Fondazione Policlinico Tor Vergata, University of Rome Tor Vergata, Rome, Italy.
J Clin Ultrasound ; 51(4): 639-643, 2023 May.
Article en En | MEDLINE | ID: mdl-36305509
OBJECTIVES: To assess cerebral growth and the development of fetal cortex using neurosonography in fetuses from pregnancies experiencing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) according to infection timing. METHODS: Pregnancies with by SARS-CoV-2 during first and second trimesters were prospectively studied and matched with unaffected controls. Enclosed women underwent neurosonography at 30-34 weeks of gestation and corpus callosum (CC) and cerebellar vermis (CV) lengths measured. Further Sylvian fissure (SF), insula. Parieto-occipital fissure (POF), and calcarine sulci fissures (CSF) depths were obtained. The ultrasonographic variables considered were normalized with fetal head size. RESULTS: One hundred and seventy four consecutive pregnancies experiencing SARS COV 2 infection (81 before 14 weeks and 93 later) and 131 not affected pregnancies were considered. General and pregnancy characteristics were similar between the three groups of women. No significant differences existed in CC and CV lengths across groups. Similarly, insula, SF, POF And CSF depth did not result changed in fetuses of affected mothers. CONCLUSIONS: SARS-CoV-2 infection does nor resulted associate with differential fetal cortical development or brain growth in mildly symptomatic pregnant women. This information may be useful to reassure infected mothers on the health of their fetuses.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Clin Ultrasound Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Female / Humans / Pregnancy Idioma: En Revista: J Clin Ultrasound Año: 2023 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos