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Design of fast-onset antidepressant by dissociating SERT from nNOS in the DRN.
Sun, Nan; Qin, Ya-Juan; Xu, Chu; Xia, Tian; Du, Zi-Wei; Zheng, Li-Ping; Li, An-An; Meng, Fan; Zhang, Yu; Zhang, Jing; Liu, Xiao; Li, Ting-You; Zhu, Dong-Ya; Zhou, Qi-Gang.
Afiliación
  • Sun N; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Qin YJ; Jiangsu Province Key Laboratory of Anesthesiology, Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application, NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou Medical University, Xuzhou 221004, China.
  • Xu C; Department of Pharmacochemistry, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Xia T; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Du ZW; Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing 210042, China.
  • Zheng LP; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Li AA; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Meng F; Department of Pharmacochemistry, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Zhang Y; Jiangsu Key Laboratory of Brain Disease and Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xu Zhou 221004, China.
  • Zhang J; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Liu X; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Li TY; State Key Laboratory of Reproductive Medicine, Department of Clinic Pharmacology, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
  • Zhu DY; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
  • Zhou QG; Department of Pharmacochemistry, School of Pharmacy, Nanjing Medical University, Nanjing 211166, China.
Science ; 378(6618): 390-398, 2022 10 28.
Article en En | MEDLINE | ID: mdl-36302033
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Trastorno Depresivo Mayor / Óxido Nítrico Sintasa de Tipo I / Proteínas de Transporte de Serotonina en la Membrana Plasmática / Núcleo Dorsal del Rafe / Antidepresivos Límite: Animals Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diseño de Fármacos / Trastorno Depresivo Mayor / Óxido Nítrico Sintasa de Tipo I / Proteínas de Transporte de Serotonina en la Membrana Plasmática / Núcleo Dorsal del Rafe / Antidepresivos Límite: Animals Idioma: En Revista: Science Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos