Combining curcumin and aspirin ameliorates preeclampsia-like symptoms by inhibiting the placental TLR4/NF-&#954;B signaling pathway in rats.

Ju, Yaru; Feng, Yan; Yang, Yanjing; Hou, Xiaolin; Zhang, Xiaofeng; Zhu, Xihui; Wang, Yage; Yang, Meiliu

Combining curcumin and aspirin ameliorates preeclampsia-like symptoms by inhibiting the placental TLR4/NF-κB signaling pathway in rats.

Ju, Yaru; Feng, Yan; Yang, Yanjing; Hou, Xiaolin; Zhang, Xiaofeng; Zhu, Xihui; Wang, Yage; Yang, Meiliu.

Afiliación

Ju Y; Perinatal Center, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
Feng Y; Department of Neurosurgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Yang Y; Perinatal Center, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
Hou X; Prenatal Diagnostic, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
Zhang X; Department of Obstetrics, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
Zhu X; Perinatal Center, The Fourth Hospital of Shijiazhuang, Shijiazhuang, China.
Wang Y; Department of Obstetrics, Gaocheng District Hospital of Traditional Chinese and Western Medicine, Shijiazhuang, China.
Yang M; Department of Biology, Hengshui University, Hengshui, China.

J Obstet Gynaecol Res ; 49(1): 128-140, 2023 Jan.

Article en En | MEDLINE | ID: mdl-36288911

Asunto(s)

Curcumina; Preeclampsia; Humanos; Ratas; Femenino; Embarazo; Animales; Aspirina/farmacología; Aspirina/uso terapéutico; FN-kappa B/metabolismo; Placenta/metabolismo; Curcumina/farmacología; Curcumina/metabolismo; Curcumina/uso terapéutico; Receptor Toll-Like 4/metabolismo; Receptor Toll-Like 4/uso terapéutico; Factor de Crecimiento Placentario/metabolismo; Transducción de Señal; Proteinuria/tratamiento farmacológico

Palabras clave

TLR4/NF-κB; aspirin; curcumin; inflammation; oxidative stress; preeclampsia

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Preeclampsia / Curcumina Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Female / Humans / Pregnancy Idioma: En Revista: J Obstet Gynaecol Res Asunto de la revista: GINECOLOGIA / OBSTETRICIA Año: 2023 Tipo del documento: Article País de afiliación: China Pais de publicación: Australia

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