Your browser doesn't support javascript.
loading
Sleep disturbances and restless legs syndrome in postmenopausal women with early breast cancer given adjuvant aromatase inhibitor therapy.
Pedersini, Rebecca; di Mauro, Pierluigi; Amoroso, Vito; Castronovo, Vincenza; Zamparini, Manuel; Monteverdi, Sara; Laini, Lara; Schivardi, Greta; Cosentini, Deborah; Grisanti, Salvatore; Marelli, Sara; Ferini Strambi, Luigi; Berruti, Alfredo.
Afiliación
  • Pedersini R; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy; SSVD Breast Unit, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • di Mauro P; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy. Electronic address: p.dimauro001@unibs.it.
  • Amoroso V; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Castronovo V; Sleep Disorders Center, Department of Clinical Neurosciences, San Raffaele Hospital and University Vita-Salute San Raffaele, Milan, Italy.
  • Zamparini M; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Monteverdi S; Santa Chiara Hospital, Trento, Italy.
  • Laini L; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Schivardi G; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Cosentini D; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Grisanti S; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
  • Marelli S; Sleep Disorders Center, Department of Clinical Neurosciences, San Raffaele Hospital and University Vita-Salute San Raffaele, Milan, Italy.
  • Ferini Strambi L; Sleep Disorders Center, Department of Clinical Neurosciences, San Raffaele Hospital and University Vita-Salute San Raffaele, Milan, Italy.
  • Berruti A; Medical Oncology Department, ASST-Spedali Civili of Brescia, Brescia, Italy.
Breast ; 66: 162-168, 2022 Dec.
Article en En | MEDLINE | ID: mdl-36288635
INTRODUCTION: Whether adjuvant therapy with aromatase inhibitors (AIs) causes sleep disturbances or not in postmenopausal women with early breast cancer (EBC) is still a controversial issue. METHODS: Between March 2014 and November 2017, validated questionnaires for assessing insomnia, anxiety, depression, quality of life (QoL) and restless legs syndrome (RLS) were administered to 160 EBC patients at baseline and after 3, 6, 12, and 24 months of AI therapy. RESULTS: AI therapy significantly decreased the patients' QoL, but did not influence insomnia, anxiety or depression. However, it significantly increased the frequency and severity of RLS. Patients with RLS at baseline (19%) or who developed RLS during AI therapy (26.3%) reported statistically lower quality of sleep, higher anxiety and depression, and worse QoL compared to patients who never reported RLS (54.7%). CONCLUSION: Although AI therapy does not affect sleep quality, it may increase RLS frequency. The presence of RLS could identify a group of EBC patients who may benefit from psychological support.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de las Piernas Inquietas / Trastornos del Sueño-Vigilia / Neoplasias de la Mama / Trastornos del Inicio y del Mantenimiento del Sueño Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Breast Asunto de la revista: ENDOCRINOLOGIA / NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Síndrome de las Piernas Inquietas / Trastornos del Sueño-Vigilia / Neoplasias de la Mama / Trastornos del Inicio y del Mantenimiento del Sueño Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Breast Asunto de la revista: ENDOCRINOLOGIA / NEOPLASIAS Año: 2022 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Países Bajos