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[ACTIV SARS-CoV-2 registry (Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients). Assessment of impact of combined original comorbid diseases in patients with COVID-19 on the prognosis].
Arutyunov, G P; Tarlovskaya, E I; Arutyunov, A G; Belenkov, Y N; Konradi, A O; Lopatin, Y M; Rebrov, A P; Tereshchenko, S N; Chesnikova, A I; Hayrapetyan, H G; Babin, A P; Bakulin, I G; Bakulina, N V; Balykova, L A; Blagonravova, A S; Boldina, M V; Vaisberg, A R; Galyavich, A S; Gomonova, V V; Grigorieva, N Y; Gubareva, I V; Demko, I V; Evzerikhina, A V; Zharkov, A V; Kamilova, U K; Kim, Z F; Kuznetsova, T Y; Lareva, N V; Makarova, E V; Malchikova, S V; Nedogoda, S V; Petrova, M M; Pochinka, I G; Protasov, K V; Protsenko, D N; Ruzanau, D Y; Sayganov, S A; Sarybaev, A S; Selezneva, N M; Sugraliev, A B; Fomin, I V; Khlynova, O V; Chizhova, O Y; Shaposhnik, I I; Sh'ukarev, D A; Abdrahmanova, А K; Avetisian, S A; Avoyan, H G; Azarian, K K; Aimakhanova, G T.
Afiliación
  • Arutyunov GP; Eurasian Association of Therapists.
  • Tarlovskaya EI; Pirogov Russian National Research Medical University.
  • Arutyunov AG; Eurasian Association of Therapists.
  • Belenkov YN; Privolzhsky Research Medical University.
  • Konradi AO; Eurasian Association of Therapists.
  • Lopatin YM; Pirogov Russian National Research Medical University.
  • Rebrov AP; Sechenov First Moscow State Medical University (Sechenov University).
  • Tereshchenko SN; Almazov National Medical Research Centre.
  • Chesnikova AI; Volgograd State Medical University.
  • Hayrapetyan HG; Saratov State Medical University named after V.I. Razumovsky.
  • Babin AP; National Medical Research Center of Cardiology.
  • Bakulin IG; Rostov State Medical University.
  • Bakulina NV; "Erebouni" Cardiology Center.
  • Balykova LA; Nicolae Testemitanu State University of Medicine and Pharmacy.
  • Blagonravova AS; Mechnikov North-Western State Medical University.
  • Boldina MV; Mechnikov North-Western State Medical University.
  • Vaisberg AR; Ogarev Mordovia State University.
  • Galyavich AS; Privolzhsky Research Medical University.
  • Gomonova VV; Privolzhsky Research Medical University.
  • Grigorieva NY; Privolzhsky Research Medical University.
  • Gubareva IV; Republican Center for Cardiovascular Diseases of Interregional Clinical Diagnostic Center.
  • Demko IV; Kazan State Medical University.
  • Evzerikhina AV; Mechnikov North-Western State Medical University.
  • Zharkov AV; Lobachevsky State University.
  • Kamilova UK; Samara State Medical University.
  • Kim ZF; Regional Clinical Hospital.
  • Kuznetsova TY; Krasnogorsk City Hospital №1.
  • Lareva NV; Kirovsk Interdisrict Hospital.
  • Makarova EV; Republican Specialized Scientific and Practical Medical Center for Therapy and Medical Rehabilitation.
  • Malchikova SV; City Clinical Hospital №7.
  • Nedogoda SV; Petrozavodsk State University.
  • Petrova MM; Chita State Medical Academy.
  • Pochinka IG; Privolzhsky Research Medical University.
  • Protasov KV; Kirov State Medical University.
  • Protsenko DN; Volgograd State Medical University.
  • Ruzanau DY; Voino-Yasenetsky Krasnoyarsk State Medical University.
  • Sayganov SA; Privolzhsky Research Medical University.
  • Sarybaev AS; City Clinical Hospital №13 of.
  • Selezneva NM; Irkutsk State Medical Academy of Postgraduate Education - Branch of Russian Medical Academy of Continuous Professional Education.
  • Sugraliev AB; Moscow City Clinical Hospital №40.
  • Fomin IV; Gomel State Medical University.
  • Khlynova OV; Mechnikov North-Western State Medical University.
  • Chizhova OY; Mirrakhimov National Center of Cardiology and Therapy.
  • Shaposhnik II; Ogarev Mordovia State University.
  • Sh'ukarev DA; Asfendiyarov Kazakh National Medical University.
  • Abdrahmanova АK; Privolzhsky Research Medical University.
  • Avetisian SA; Vagner Perm State Medical University.
  • Avoyan HG; Mechnikov North-Western State Medical University.
  • Azarian KK; South Ural State Medical University.
  • Aimakhanova GT; Kirovsk Interdisrict Hospital.
Ter Arkh ; 94(1): 32-47, 2022 Jan 15.
Article en Ru | MEDLINE | ID: mdl-36286918
AIM: Study the impact of various combinations of comorbid original diseases in patients infected with COVID-19 later on the disease progression and outcomes of the new coronavirus infection. MATERIALS AND METHODS: The ACTIV registry was created on the Eurasian Association of Therapists initiative. 5,808 patients have been included in the registry: men and women with COVID-19 treated at hospital or at home. CLINICALTRIALS: gov ID NCT04492384. RESULTS: Most patients with COVID-19 have original comorbid diseases (oCDs). Polymorbidity assessed by way of simple counting of oCDs is an independent factor in negative outcomes of COVID-19. Search for most frequent combinations of 2, 3 and 4 oCDs has revealed absolute domination of cardiovascular diseases (all possible variants). The most unfavorable combination of 2 oCDs includes atrial hypertension (AH) and chronic heart failure (CHF). The most unfavorable combination of 3 oCDs includes AH, coronary heart disease (CHD) and CHF; the worst combination of 4 oCDs includes AH, CHD, CHF and diabetes mellitus. Such combinations increased the risk of lethal outcomes 3.963, 4.082 and 4.215 times respectively. CONCLUSION: Polymorbidity determined by way of simple counting of diseases may be estimated as a factor in the lethal outcome risk in the acute phase of COVID-19 in real practice. Most frequent combinations of 2, 3 and 4 diseases in patients with COVID-19 primarily include cardiovascular diseases (AH, CHD and CHF), diabetes mellitus and obesity. Combinations of such diseases increase the COVID-19 lethal outcome risk.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Enfermedad Coronaria / Diabetes Mellitus / Enfermedades no Transmisibles / COVID-19 / Insuficiencia Cardíaca / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: Ru Revista: Ter Arkh Año: 2022 Tipo del documento: Article Pais de publicación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Enfermedad Coronaria / Diabetes Mellitus / Enfermedades no Transmisibles / COVID-19 / Insuficiencia Cardíaca / Hipertensión Tipo de estudio: Diagnostic_studies / Etiology_studies / Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: Ru Revista: Ter Arkh Año: 2022 Tipo del documento: Article Pais de publicación: Rusia