Your browser doesn't support javascript.
loading
Factors associated with the use of salvage whole brain radiation therapy versus salvage stereotactic radiosurgery after initial stereotactic radiosurgery for brain metastases.
Soni, Yash S; Rich, Benjamin J; Kwon, Deukwoo; Zhao, Wei; John, Danny L; Seldon, Crystal; Meshman, Jessica; Benveniste, Ronald; Komotar, Ricardo J; de la Fuente, Macarena; Guillermo Prieto, Maria Del Pilar; Azzam, Gregory; Mellon, Eric A; Benjamin, Carolina G; Diwanji, Tejan.
Afiliación
  • Soni YS; University of Miami Miller School of Medicine, Miami, FL, USA.
  • Rich BJ; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Kwon D; Department of Public Health Sciences, Biostatistics and Bioinformatics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Zhao W; Department of Public Health Sciences, Biostatistics and Bioinformatics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.
  • John DL; University of Miami Miller School of Medicine, Miami, FL, USA.
  • Seldon C; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Meshman J; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Benveniste R; Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Komotar RJ; Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA.
  • de la Fuente M; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Guillermo Prieto MDP; Department of Neurology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Azzam G; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Mellon EA; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Benjamin CG; Department of Neurosurgery, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Diwanji T; Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.
J Radiosurg SBRT ; 8(2): 85-94, 2022.
Article en En | MEDLINE | ID: mdl-36275132
Objectives: Patients undergoing stereotactic radiosurgery (SRS) for brain metastases require additional radiation for relapse. Our objective is to determine the factors associated with salvage SRS versus whole brain radiation therapy (WBRT) for salvage of first intracranial failure (ICF) after upfront SRS. Method: We identified a cohort of 110 patients with brain metastases treated with SRS in the definitive or postoperative setting followed by subsequent salvage WBRT or SRS at least one month after initial SRS. Clinical and demographic characteristics were retrospectively recorded. Results: 78 Patients received SRS and 32 patients received WBRT at the time of first ICF. On multivariate analysis (MVA) factors associated with decreased use of salvage SRS were male gender (p=0.044) and local progression (p<0.001). Conclusions: Local progression and male gender were the strongest factors associated with selection of salvage WBRT. Possible etiologies of this difference could be provider or patient driven, but warrant further exploration.
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Radiosurg SBRT Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Radiosurg SBRT Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos