The healthy heart does not control a specific cardiac output: a plea for a new interpretation of normal cardiac function.
Am J Physiol Heart Circ Physiol
; 323(6): H1239-H1243, 2022 12 01.
Article
en En
| MEDLINE
| ID: mdl-36269649
The current evidence suggests that the healthy heart does not sense the optimal cardiac output (QÌ) because the different organ systems that influence cardiac function do not interact to adjust their individual responses toward a specific QÌ. Consequently, it is conceivable that the complex cycle of cardiac contraction and relaxation must occur for reasons other than to produce a specific target QÌ and that there is likely a yet undiscovered overarching principle in the cardiovascular system that explains the combined effects of the prevailing preload, afterload, and contractility. Future research should embrace the possibility of a different purpose to cardiac function than previously assumed and examine the biological capacity of this fascinating organ accordingly.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Corazón
/
Contracción Miocárdica
Idioma:
En
Revista:
Am J Physiol Heart Circ Physiol
Asunto de la revista:
CARDIOLOGIA
/
FISIOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Alemania
Pais de publicación:
Estados Unidos