Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVC<sub>Env</sub>) covalently complexed to two-domain CD4<sup>S60C</sup> elicits cross-clade neutralizing antibodies in New Zealand white rabbits.

Tumba, Nancy L; Owen, Gavin R; Killick, Mark A; Papathanasopoulos, Maria A

Immunization with HIV-1 trimeric SOSIP.664 BG505 or founder virus C (FVC_Env) covalently complexed to two-domain CD4^S60C elicits cross-clade neutralizing antibodies in New Zealand white rabbits.

Tumba, Nancy L; Owen, Gavin R; Killick, Mark A; Papathanasopoulos, Maria A.

Afiliación

Tumba NL; HIV Pathogenesis Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Owen GR; HIV Pathogenesis Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Killick MA; HIV Pathogenesis Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Papathanasopoulos MA; HIV Pathogenesis Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Vaccine X ; 12: 100222, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36262212

Palabras clave

Broadly neutralizing antibodies; Covalent complexes; Envelope glycoprotein trimers; HIV-1 vaccine immunogens; Immunogen design; New Zealand White rabbits

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Vaccine X Año: 2022 Tipo del documento: Article País de afiliación: Sudáfrica Pais de publicación: Reino Unido

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