Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1&#945; signaling pathway-mediated inflammation, apoptosis, and oxidative stress.

Li, Jinjin; Li, Jie; Fang, Hongbo; Yang, Hang; Wu, Tianchun; Shi, Xiaoyi; Pang, Chun

Isolongifolene alleviates liver ischemia/reperfusion injury by regulating AMPK-PGC1α signaling pathway-mediated inflammation, apoptosis, and oxidative stress.

Li, Jinjin; Li, Jie; Fang, Hongbo; Yang, Hang; Wu, Tianchun; Shi, Xiaoyi; Pang, Chun.

Afiliación

Li J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Li J; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Fang H; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yang H; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Wu T; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Shi X; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Pang C; Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Electronic address: wader1026@sina.cn.

Int Immunopharmacol ; 113(Pt A): 109185, 2022 Dec.

Article en En | MEDLINE | ID: mdl-36252482

Asunto(s)

Hepatopatías; Daño por Reperfusión; Animales; Ratones; Proteínas Quinasas Activadas por AMP/metabolismo; Proteína X Asociada a bcl-2/metabolismo; Antioxidantes/farmacología; Antioxidantes/uso terapéutico; Antioxidantes/metabolismo; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/metabolismo; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/farmacología; Daño por Reperfusión/metabolismo; Apoptosis; Estrés Oxidativo; Hígado; Transducción de Señal; Inflamación/tratamiento farmacológico; Inflamación/metabolismo; Proteínas Proto-Oncogénicas c-bcl-2/metabolismo; Hepatopatías/metabolismo

Palabras clave

AMPK-PGC1α pathway; Apoptosis; Inflammation; Isolongifolene; Liver ischemia/reperfusion injury; Oxidative stress

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Daño por Reperfusión / Hepatopatías Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China Pais de publicación: Países Bajos

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