Improving Interpretability in Machine Diagnosis: Detection of Geographic Atrophy in OCT Scans.

Shi, Xiaoshuang; Keenan, Tiarnan D L; Chen, Qingyu; De Silva, Tharindu; Thavikulwat, Alisa T; Broadhead, Geoffrey; Bhandari, Sanjeeb; Cukras, Catherine; Chew, Emily Y; Lu, Zhiyong

Shi, Xiaoshuang; Keenan, Tiarnan D L; Chen, Qingyu; De Silva, Tharindu; Thavikulwat, Alisa T; Broadhead, Geoffrey; Bhandari, Sanjeeb; Cukras, Catherine; Chew, Emily Y; Lu, Zhiyong.

Afiliación

Shi X; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
Keenan TDL; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Chen Q; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.
De Silva T; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Thavikulwat AT; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Broadhead G; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Bhandari S; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Cukras C; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Chew EY; Division of Epidemiology and Clinical Applications, National Eye Institute, National Institutes of Health, Bethesda, Maryland.
Lu Z; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland.

Ophthalmol Sci ; 1(3): 100038, 2021 Sep.

Article en En | MEDLINE | ID: mdl-36247813

Palabras clave

AMD, age-related macular degeneration; AREDS2, Age-Related Eye Disease Study 2; AUC, area under curve; CAM, class activation mapping; CFP, color fundus photograph; CNN, convolutional neural network; Deep learning; GA detection; GA, geographic atrophy; Grad-CAM, gradient-weighted class activation mapping; I3D, Inflated 3D Convnet; Interpretable; OCT; PR, precision-recall; PR-AUC, area under PR curve; ROC, receiver operating characteristic; RPE, retinal pigment epithelium; SD, spectral-domain; XAI, explainable artificial intelligence; cRORA, complete retinal pigment epithelium and outer retinal atrophy

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Diagnostic_studies / Prognostic_studies Idioma: En Revista: Ophthalmol Sci Año: 2021 Tipo del documento: Article Pais de publicación: Países Bajos

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