SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.

Jha, Atimukta; Ahad, Abdul; Mishra, Gyan Prakash; Sen, Kaushik; Smita, Shuchi; Minz, Aliva Prity; Biswas, Viplov Kumar; Tripathy, Archana; Senapati, Shantibhushan; Gupta, Bhawna; Acha-Orbea, Hans; Raghav, Sunil Kumar

Jha, Atimukta; Ahad, Abdul; Mishra, Gyan Prakash; Sen, Kaushik; Smita, Shuchi; Minz, Aliva Prity; Biswas, Viplov Kumar; Tripathy, Archana; Senapati, Shantibhushan; Gupta, Bhawna; Acha-Orbea, Hans; Raghav, Sunil Kumar.

Afiliación

Jha A; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Ahad A; Manipal Academy of Higher Education, Manipal, KA, India.
Mishra GP; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Sen K; Manipal Academy of Higher Education, Manipal, KA, India.
Smita S; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Minz AP; Department of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, India.
Biswas VK; Regional Centre for Biotechnology, NCR Biotech Science Cluster, Haryana, India.
Tripathy A; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Senapati S; Manipal Academy of Higher Education, Manipal, KA, India.
Gupta B; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Acha-Orbea H; Immuno-genomics & Systems Biology laboratory, Institute of Life Sciences (ILS), Bhubaneswar, OR, India.
Raghav SK; Department of Biotechnology, Kalinga Institute of Industrial Technology (KIIT), Bhubaneswar, India.

Front Immunol ; 13: 910705, 2022.

Article en En | MEDLINE | ID: mdl-36238311

Asunto(s)

Interleucina-10; Interleucina-6; Animales; Linfocitos T CD8-positivos/metabolismo; Citocinas/metabolismo; Células Dendríticas/metabolismo; Interleucina-10/metabolismo; Interleucina-12/metabolismo; Interleucina-23/metabolismo; Interleucina-6/metabolismo; Ratones; Co-Represor 1 de Receptor Nuclear/genética; Co-Represor 1 de Receptor Nuclear/metabolismo; Co-Represor 2 de Receptor Nuclear; Factor de Transcripción STAT3; Serina-Treonina Quinasas TOR/metabolismo

Palabras clave

Nr4a1; SMRT and NCoR1; Th1/Th17 T-cell response; comparative genomic and transcriptomic (RNA-seq and ChIP-seq); dendritic cells; mTOR-STAT3-IL10 signaling

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interleucina-6 / Interleucina-10 Límite: Animals Idioma: En Revista: Front Immunol Año: 2022 Tipo del documento: Article País de afiliación: India Pais de publicación: Suiza

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