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The Role of Diet and Gut Microbiome in Multiple Sclerosis.
Jayasinghe, Maleesha; Prathiraja, Omesh; Kayani, Abdul Mueez Alam; Jena, Rahul; Caldera, Dilushini; Silva, Minollie Suzanne; Singhal, Malay; Pierre, Jimmy.
Afiliación
  • Jayasinghe M; Medicine, Nanjing Medical University, Nanjing, CHN.
  • Prathiraja O; Medicine and Surgery, Nanjing Medical University, Nanjing, CHN.
  • Kayani AMA; Medicine and Surgery, Allama Iqbal Medical College, Lahore, PAK.
  • Jena R; Medicine, Bharati Vidyapeeth Medical College/Bharati Hospital, Pune, IND.
  • Caldera D; Internal Medicine, Nanjing Medical University, Nanjing, CHN.
  • Silva MS; Medicine and Surgery, Nanjing Medical University, Nanjing, CHN.
  • Singhal M; Internal Medicine, Mahatma Gandhi Memorial Medical College, Indore, IND.
  • Pierre J; Internal Medicine, Nanjing Medical University, Nanjing, CHN.
Cureus ; 14(9): e28975, 2022 Sep.
Article en En | MEDLINE | ID: mdl-36237764
Multiple sclerosis (MS) is a chronic demyelinating condition of the central nervous system (CNS) characterized by immune-mediated damage to the myelin sheath of nerve cells. Genetic and environmental factors are believed to play a significant role. Unfortunately, the knowledge of therapeutic modalities in MS remains very limited, necessitating the need for novel therapeutic strategies. In the previous decade, there has been an influx of studies on the gut microbiome and its link to various neurological conditions, including MS. Various diets may have favorable effects on the gut microflora and may significantly alter the progression and outcomes of MS. Thus, identifying the merits of various diets and modulating them according to the specific nutritional requirements of MS patients can go a long way toward slowing the progression of the disease. Nutritional interventions and the use of the gut microbiome as diagnostic and therapeutic modalities open a host of new possibilities regarding the disease. In this review, we investigate the role of diet and the gut microbiome in the progression of MS. The functions of the gut-brain axis, antioxidants, vitamins, obesity, and various diets are also covered in this article.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cureus Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Cureus Año: 2022 Tipo del documento: Article Pais de publicación: Estados Unidos