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Prevalence and Risk Factor Analysis of Post-Intensive Care Syndrome in Patients with COVID-19 Requiring Mechanical Ventilation: A Multicenter Prospective Observational Study.
Hatakeyama, Junji; Inoue, Shigeaki; Liu, Keibun; Yamakawa, Kazuma; Nishida, Takeshi; Ohshimo, Shinichiro; Hashimoto, Satoru; Kanda, Naoki; Maruyama, Shuhei; Ogata, Yoshitaka; Kawakami, Daisuke; Shimizu, Hiroaki; Hayakawa, Katsura; Tanaka, Aiko; Oshima, Taku; Fuchigami, Tatsuya; Yawata, Hironori; Oe, Kyoji; Kawauchi, Akira; Yamagata, Hidehiro; Harada, Masahiro; Sato, Yuichi; Nakamura, Tomoyuki; Sugiki, Kei; Hakozaki, Takahiro; Beppu, Satoru; Anraku, Masaki; Kato, Noboru; Iwashita, Tomomi; Kamijo, Hiroshi; Kitagawa, Yuichiro; Nagashima, Michio; Nishimaki, Hirona; Tokuda, Kentaro; Nishida, Osamu; Nakamura, Kensuke.
Afiliación
  • Hatakeyama J; Department of Emergency and Critical Care Medicine, National Hospital Organization Tokyo Medical Center, Tokyo 152-8902, Japan.
  • Inoue S; Department of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
  • Liu K; Department of Disaster and Emergency Medicine, School of Medicine, Kobe University, Kobe 650-0017, Japan.
  • Yamakawa K; Critical Care Research Group, The Prince Charles Hospital, Brisbane, QLD 4032, Australia.
  • Nishida T; Department of Emergency and Critical Care Medicine, Osaka Medical and Pharmaceutical University, Osaka 569-8686, Japan.
  • Ohshimo S; Division of Trauma and Surgical Critical Care, Osaka General Medical Center, Osaka 558-8558, Japan.
  • Hashimoto S; Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
  • Kanda N; Department of Intensive Care Medicine, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan.
  • Maruyama S; Division of General Internal Medicine, Jichi Medical University Hospital, Tochigi 329-0498, Japan.
  • Ogata Y; Department of Emergency and Critical Care Medicine, Kansai Medical University Medical Center, Osaka 570-8507, Japan.
  • Kawakami D; Department of Critical Care Medicine, Yao Tokushukai General Hospital, Osaka 581-0011, Japan.
  • Shimizu H; Department of Anesthesia and Critical Care, Kobe City Medical Center General Hospital, Kobe 650-0047, Japan.
  • Hayakawa K; Acute Care Medical Center, Hyogo Prefectural Kakogawa Medical Center, Kakogawa 675-8555, Japan.
  • Tanaka A; Department of Emergency and Critical Care Medicine, Saitama Red Cross Hospital, Saitama 330-8553, Japan.
  • Oshima T; Department of Anesthesiology and Intensive Care Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.
  • Fuchigami T; Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba 260-8677, Japan.
  • Yawata H; Intensive Care Unit, University of the Ryukyus Hospital, Nishihara 903-0215, Japan.
  • Oe K; Department of Emergency and Critical Care Medicine, Japanese Red Cross Kyoto Daiichi Hospital, Kyoto 605-0981, Japan.
  • Kawauchi A; Department of Intensive Care Medicine, Asahi General Hospital, Chiba 289-2511, Japan.
  • Yamagata H; Japanese Red Cross Maebashi Hospital, Advanced Medical Emergency Department and Critical Care Center, Maebashi 371-0811, Japan.
  • Harada M; Advanced Critical Care and Emergency Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
  • Sato Y; Department of Emergency and Critical Care, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
  • Nakamura T; Critical Care and Emergency Center, Metropolitan Tama General Medical Center, Tokyo 183-8524, Japan.
  • Sugiki K; Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, Nagoya 470-1192, Japan.
  • Hakozaki T; Department of Intensive Care Medicine, Yokohama City Minato Red Cross Hospital, Yokohama 231-8682, Japan.
  • Beppu S; Department of Anesthesiology, Fukushima Medical University, Fukushima 960-1295, Japan.
  • Anraku M; Department of Emergency and Critical Care Medicine, National Hospital Organization Kyoto Medical Center, Kyoto 612-8555, Japan.
  • Kato N; Department of Thoracic Surgery, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo 173-0015, Japan.
  • Iwashita T; Department of Emergency and Critical Care Medicine, Yodogawa Christian Hospital, Osaka 533-0024, Japan.
  • Kamijo H; Department of Emergency and Critical Care Center, Nagano Red Cross Hospital, Nagano 380-8582, Japan.
  • Kitagawa Y; Department of Emergency and Critical Care Medicine, Shinshu University Hospital, Nagano 390-8621, Japan.
  • Nagashima M; Emergency and Disaster Medicine, Gifu University School of Medicine Graduate School of Medicine, Gifu 501-1194, Japan.
  • Nishimaki H; Department of Intensive Care Medicine, Tokyo Medical and Dental University, Tokyo 113-8519, Japan.
  • Tokuda K; Department of Anesthesiology and Pain Medicine, Juntendo University, Tokyo 113-8431, Japan.
  • Nishida O; Department of Anesthesiology, Tohoku University Hospital, Sendai 980-8574, Japan.
  • Nakamura K; Intensive Care Unit, Kyushu University Hospital, Fukuoka 812-8582, Japan.
J Clin Med ; 11(19)2022 Sep 28.
Article en En | MEDLINE | ID: mdl-36233627
INTRODUCTION: Post-intensive care syndrome (PICS) is an emerging problem in critically ill patients and the prevalence and risk factors are unclear in patients with severe coronavirus disease 2019 (COVID-19). This multicenter prospective observational study aimed to investigate the prevalence and risk factors of PICS in ventilated patients with COVID-19 after ICU discharge. METHODS: Questionnaires were administered twice in surviving patients with COVID-19 who had required mechanical ventilation, concerning Barthel Index, Short-Memory Questionnaire, and Hospital Anxiety and Depression Scale scores. The risk factors for PICS were examined using a multivariate logistic regression analysis. RESULTS: The first and second PICS surveys were obtained at 5.5 and 13.5 months (mean) after ICU discharge, with 251 and 209 patients completing the questionnaires and with a prevalence of PICS of 58.6% and 60.8%, respectively, along with the highest percentages of cognitive impairment. Delirium (with an odds ratio of (OR) 2.34, 95% CI 1.1-4.9, and p = 0.03) and the duration of mechanical ventilation (with an OR of 1.29, 95% CI 1.05-1.58, and p = 0.02) were independently identified as the risk factors for PICS in the first PICS survey. CONCLUSION: Approximately 60% of the ventilated patients with COVID-19 experienced persistent PICS, especially delirium, and required longer mechanical ventilation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Idioma: En Revista: J Clin Med Año: 2022 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Suiza