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Childhood Predictors of Long-Term Tic Severity and Tic Impairment in Tourette's Disorder.
Ricketts, Emily J; Woods, Douglas W; Espil, Flint M; McGuire, Joseph F; Stiede, Jordan T; Schild, Jennifer; Yadegar, Mina; Bennett, Shannon M; Specht, Matthew W; Chang, Susanna; Scahill, Lawrence; Wilhelm, Sabine; Peterson, Alan L; Walkup, John T; Piacentini, John.
Afiliación
  • Ricketts EJ; University of California, Los Angeles. Electronic address: ericketts@mednet.ucla.edu.
  • Woods DW; Marquette University.
  • Espil FM; Stanford University.
  • McGuire JF; Johns Hopkins University School of Medicine.
  • Stiede JT; Marquette University.
  • Schild J; Weill Cornell Medicine; Suffolk University.
  • Yadegar M; Rogers Behavioral Health.
  • Bennett SM; Weill Cornell Medicine.
  • Specht MW; Weill Cornell Medicine.
  • Chang S; University of California, Los Angeles.
  • Scahill L; Marcus Autism Center, Emory University School of Medicine.
  • Wilhelm S; Massachusetts General Hospital/Harvard Medical School.
  • Peterson AL; University of Texas Health Science Center at San Antonio.
  • Walkup JT; Ann and Robert H. Lurie Children's Hospital of Chicago; Northwestern University Feinberg School of Medicine.
  • Piacentini J; University of California, Los Angeles.
Behav Ther ; 53(6): 1250-1264, 2022 11.
Article en En | MEDLINE | ID: mdl-36229120
Tics peak in late childhood and decline during adolescence. Yet, for some with Tourette's disorder, tics persist into adulthood. We evaluated childhood predictors of adult tic severity and tic impairment, and change over time. Eighty adolescents/adults were evaluated 11 years following a randomized-controlled trial of behavior therapy. An independent evaluator rated tic severity and tic impairment at baseline, posttreatment, and long-term follow-up. At baseline, parents completed demographics/medical history, and youth tic, internalizing, and externalizing symptom ratings. Youth rated premonitory urge severity and family functioning. After controlling for prior tic treatment effects, female sex and higher tic severity predicted higher tic severity in adulthood; and female sex, no stimulant medication use, higher tic severity, and poorer family functioning predicted higher tic impairment. Higher tic severity and premonitory urge severity predicted smaller reductions in tic severity, whereas higher externalizing symptoms predicted greater reduction in tic severity. Female sex predicted smaller reduction in tic impairment, and externalizing symptoms predicted greater reduction in tic impairment. Female sex and childhood tic severity are important predictors of tic severity and tic impairment in adulthood. Family functioning, premonitory urge severity, and tic severity are important modifiable targets for early or targeted intervention to improve long-term outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de Tic / Síndrome de Tourette / Tics Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans Idioma: En Revista: Behav Ther Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de Tic / Síndrome de Tourette / Tics Tipo de estudio: Clinical_trials / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans Idioma: En Revista: Behav Ther Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido