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Outcomes among confirmed cases and a matched comparison group in the Long-COVID in Scotland study.
Hastie, Claire E; Lowe, David J; McAuley, Andrew; Winter, Andrew J; Mills, Nicholas L; Black, Corri; Scott, Janet T; O'Donnell, Catherine A; Blane, David N; Browne, Susan; Ibbotson, Tracy R; Pell, Jill P.
Afiliación
  • Hastie CE; Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
  • Lowe DJ; Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
  • McAuley A; Emergency Department, Queen Elizabeth University Hospital, Glasgow, G52 4TF, UK.
  • Winter AJ; Public Health Scotland, Meridian Court, Glasgow, G2 6QQ, UK.
  • Mills NL; School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, UK.
  • Black C; Sandyford Sexual Health Services, NHS Greater Glasgow and Clyde, Glasgow, G3 7NB, UK.
  • Scott JT; BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, EH16 4SU, UK.
  • O'Donnell CA; Usher Institute, University of Edinburgh, Edinburgh, EH16 4UX, UK.
  • Blane DN; Aberdeen Centre for Health Data Science, University of Aberdeen, Aberdeen, AB25 2ZD, UK.
  • Browne S; Public Health Directorate, NHS Grampian, Aberdeen, AB15 6RE, UK.
  • Ibbotson TR; MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow, G61 1QH, UK.
  • Pell JP; Institute of Health and Wellbeing, University of Glasgow, Glasgow, G12 8RZ, UK.
Nat Commun ; 13(1): 5663, 2022 10 12.
Article en En | MEDLINE | ID: mdl-36224173
With increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and 18-month questionnaires and linkage to hospitalization and death records. Of the 31,486 symptomatic infections,1,856 (6%) had not recovered and 13,350 (42%) only partially. No recovery was associated with hospitalized infection, age, female sex, deprivation, respiratory disease, depression and multimorbidity. Previous symptomatic infection was associated with poorer quality of life, impairment across all daily activities and 24 persistent symptoms including breathlessness (OR 3.43, 95% CI 3.29-3.58), palpitations (OR 2.51, OR 2.36-2.66), chest pain (OR 2.09, 95% CI 1.96-2.23), and confusion (OR 2.92, 95% CI 2.78-3.07). Asymptomatic infection was not associated with adverse outcomes. Vaccination was associated with reduced risk of seven symptoms. Here we describe the nature of long-COVID and the factors associated with it.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: COVID-19 Aspecto: Patient_preference Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2022 Tipo del documento: Article Pais de publicación: Reino Unido