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Three new rotenoids from the stems of Derris elliptica and their anti-microbial activity.
Trang, Bui Thi Thu; Huong, Nguyen Thi; Anh, Nguyen Tuan; Huong, Phan Thi Thanh; Nhiem, Nguyen Xuan.
Afiliación
  • Trang BTT; Graduate University of Science and Technology, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
  • Huong NT; Faculty of Chemical Technology, Hanoi University of Industry, Hanoi, Vietnam.
  • Anh NT; Faculty of Chemical Technology, Hanoi University of Industry, Hanoi, Vietnam.
  • Huong PTT; Faculty of Chemical Technology, Hanoi University of Industry, Hanoi, Vietnam.
  • Nhiem NX; Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Nat Prod Res ; 37(16): 2704-2711, 2023.
Article en En | MEDLINE | ID: mdl-36214693
Three new rotenoids, named derieliptosides A-C (1-3), were isolated from the stems of Derris elliptica (Wall.) Benth. Their structures were determined by HR-ESI-MS and NMR spectroscopic methods. Absolute configurations of them were elucidated by analysis of ECD spectra in comparison with TD-DFT calculation. Compounds 1-3 inhibited the growth of fungus Candida albicans and selectively inhibited bacterial strains. Of these, compound 1 showed selective inhibition on the growth of Enterococcus faecalis (MIC: 37.5 µM and IC50: 10.6 µM), Staphylococcus aureus (MIC: 75 µM and IC50: 22.7 µM), and C. albicans (MIC: 37.5 µM and IC50: 11.2 µM).
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido
Texto completo
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Imprimir
XML
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nat Prod Res Año: 2023 Tipo del documento: Article País de afiliación: Vietnam Pais de publicación: Reino Unido